Elevated mean arterial pressure in the ovariectomized rat was normalized by ETA receptor antagonist therapy: Absence of cardiac hypertrophy and fibrosis

British Journal of Pharmacology

Volumn 136, Issue 5, 2002, Pages 685-692

  Mercier, Isabelle ^a   Pham Dang, Mylan ^a   Clement, Robert ^a   Gosselin, Hugues ^a   Colombo, Federico ^a   Rouleau, Jean Lucien ^b   Calderone, Angelino ^a  

^a MONTREAL HEART INSTITUTE   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Cardiac hypertrophy; Endothelin 1; Fibrosis; Hypertension; Ovariectomy

Indexed keywords

5 DIMETHYLAMINO N (3,4 DIMETHYL 5 ISOXAZOLYL) 1 NAPHTHALENESULFONAMIDE; ATRIAL NATRIURETIC FACTOR; COLLAGEN TYPE 1; COLLAGEN TYPE 3; ENDOTHELIN 1; ESTROGEN RECEPTOR; MESSENGER RNA; 5 (DIMETHYLAMINO) N (3,4 DIMETHYL 5 ISOXAZOLYL) 1 NAPHTHALENESULFONAMIDE; 5-(DIMETHYLAMINO)-N-(3,4-DIMETHYL-5-ISOXAZOLYL)-1-NAPHTHALENESULFONAMIDE; DANSYL CHLORIDE; ENDOTHELIN A RECEPTOR; ENDOTHELIN RECEPTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATROPHY; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE FIBROSIS; HEART VENTRICLE CONTRACTION; HEMODYNAMICS; MEAN ARTERIAL PRESSURE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; UTERUS; ANIMAL; BLOOD PRESSURE; COMPARATIVE STUDY; DRUG ANTAGONISM; HYPERTENSION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; STATISTICS;

ANIMAL; BLOOD PRESSURE; COMPARATIVE STUDY; DANSYL COMPOUNDS; ENDOMYOCARDIAL FIBROSIS; FEMALE; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ENDOTHELIN; SUPPORT, NON-U.S. GOV'T; ANIMALS; RECEPTOR, ENDOTHELIN A;

EID: 0035987780     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704765     Document Type: Article

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