메뉴 건너뛰기




Volumn 20, Issue 4, 2000, Pages 949-956

Blockade of angiotensin II type 1 receptor and not of endothelin receptor prevents hypertension and cardiovascular disease in transgenic (mREN2)27 rats via adrenocortical steroid-independent mechanisms

Author keywords

Angiotensin; Endothelin; Hypertension; Receptor antagonists; Target organ damage

Indexed keywords

ALDOSTERONE; ANGIOTENSIN 1 RECEPTOR; ENDOTHELIN; ENDOTHELIN RECEPTOR;

EID: 0034035143     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.20.4.949     Document Type: Article
Times cited : (49)

References (51)
  • 1
    • 0032435964 scopus 로고    scopus 로고
    • Endothelin and endothelin antagonists in hypertension
    • Schiffrin EL. Endothelin and endothelin antagonists in hypertension. J Hypertens. 1998;16:1891-1895.
    • (1998) J Hypertens , vol.16 , pp. 1891-1895
    • Schiffrin, E.L.1
  • 2
    • 0025372848 scopus 로고
    • Functional analysis of the endothelin-1 gene promoter: Evidence for an endothelial cell specific cis-acting sequence
    • Lee ME, Bloch KD, Clifford JA, Quertermous T. Functional analysis of the endothelin-1 gene promoter: evidence for an endothelial cell specific cis-acting sequence. J Biol Chem. 1990;265:10446-10450.
    • (1990) J Biol Chem , vol.265 , pp. 10446-10450
    • Lee, M.E.1    Bloch, K.D.2    Clifford, J.A.3    Quertermous, T.4
  • 3
    • 0031590298 scopus 로고    scopus 로고
    • Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: Role of ETA receptors for endothelin regulation
    • Barton M, Shaw S, d'Uscio LV, Moreau P, Luscher TF. Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: role of ETA receptors for endothelin regulation. Biochem Biophys Res Commun. 1997;238:861-865.
    • (1997) Biochem Biophys Res Commun , vol.238 , pp. 861-865
    • Barton, M.1    Shaw, S.2    D'Uscio, L.V.3    Moreau, P.4    Luscher, T.F.5
  • 4
    • 0033178254 scopus 로고    scopus 로고
    • Interactions between endothelin-1 and the renin-angiotensin-aldosterone system
    • Rossi GP, Sacchetto A, Cesari M, Pessina AC. Interactions between endothelin-1 and the renin-angiotensin-aldosterone system. Cardiovasc Res. 1999;43:300-307.
    • (1999) Cardiovasc Res , vol.43 , pp. 300-307
    • Rossi, G.P.1    Sacchetto, A.2    Cesari, M.3    Pessina, A.C.4
  • 5
    • 0025476804 scopus 로고
    • Stimulation of endothelin mRNA and secretion in rat vascular smooth muscle cells: A novel autocrine function
    • Hahn AW, Resink TJ, Scott Burden T, Powell J, Dohi Y, Buhler FR. Stimulation of endothelin mRNA and secretion in rat vascular smooth muscle cells: a novel autocrine function. Cell Regul. 1990;1:649-659.
    • (1990) Cell Regul , vol.1 , pp. 649-659
    • Hahn, A.W.1    Resink, T.J.2    Scott Burden, T.3    Powell, J.4    Dohi, Y.5    Buhler, F.R.6
  • 6
    • 0024253522 scopus 로고
    • Endothelin stimulates phospholipase C in cultured vascular smooth muscle cells
    • Resink TJ, Scott-Burden T, Buhler FR. Endothelin stimulates phospholipase C in cultured vascular smooth muscle cells. Biochem Biophys Res Comm. 1988;157:1360-1368.
    • (1988) Biochem Biophys Res Comm , vol.157 , pp. 1360-1368
    • Resink, T.J.1    Scott-Burden, T.2    Buhler, F.R.3
  • 7
    • 0027939260 scopus 로고
    • Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle
    • Sung CP, Arleth AJ, Storer BL, Ohlstein EH. Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle. J Pharmacol Exp Ther. 1994;271: 429-437.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 429-437
    • Sung, C.P.1    Arleth, A.J.2    Storer, B.L.3    Ohlstein, E.H.4
  • 8
    • 0026566370 scopus 로고
    • Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells
    • Imai T, Hirata Y, Emori T, Yanagisawa M, Masaki T, Marumo F. Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells. Hypertension. 1992;19:753-757.
    • (1992) Hypertension , vol.19 , pp. 753-757
    • Imai, T.1    Hirata, Y.2    Emori, T.3    Yanagisawa, M.4    Masaki, T.5    Marumo, F.6
  • 9
    • 0027182246 scopus 로고
    • Regulation of endothelin-1 mRNA by angiotensin II in rat heart endothelial cells
    • Chua BH, Chua CC, Diglio CA, Siu BB. Regulation of endothelin-1 mRNA by angiotensin II in rat heart endothelial cells. Biochim Biophys Acta. 1993;1178:201-206.
    • (1993) Biochim Biophys Acta , vol.1178 , pp. 201-206
    • Chua, B.H.1    Chua, C.C.2    Diglio, C.A.3    Siu, B.B.4
  • 10
    • 0027257160 scopus 로고
    • Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes
    • Ho H, Hirata Y, Adachi S, Tanaka M, Tsujino M, Koike A, Nogami A, Murumo F, Hiroe M. Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes. J Clin Invest. 1993;92:398-403.
    • (1993) J Clin Invest , vol.92 , pp. 398-403
    • Ho, H.1    Hirata, Y.2    Adachi, S.3    Tanaka, M.4    Tsujino, M.5    Koike, A.6    Nogami, A.7    Murumo, F.8    Hiroe, M.9
  • 11
    • 0028989037 scopus 로고
    • Angiotensin AT1 receptor-mediated attenuation of cardiac hypertrophy due to volume overload: Involvement of endothelin
    • Ishiye M, Umemura K, Uematsu T, Nakashima M. Angiotensin AT1 receptor-mediated attenuation of cardiac hypertrophy due to volume overload: involvement of endothelin. Eur J Pharmacol. 1995;280:11-17.
    • (1995) Eur J Pharmacol , vol.280 , pp. 11-17
    • Ishiye, M.1    Umemura, K.2    Uematsu, T.3    Nakashima, M.4
  • 13
    • 0030776737 scopus 로고    scopus 로고
    • Angiotensin II increases tissue endothelin and induces vascular hypertrophy: Reversal by ET(A)-receptor antagonist
    • Moreau P, d'Uscio LV, Shaw S, Takase H, Barton M, Luscher TF. Angiotensin II increases tissue endothelin and induces vascular hypertrophy: reversal by ET(A)-receptor antagonist. Circulation. 1997;96: 1593-1597.
    • (1997) Circulation , vol.96 , pp. 1593-1597
    • Moreau, P.1    D'Uscio, L.V.2    Shaw, S.3    Takase, H.4    Barton, M.5    Luscher, T.F.6
  • 14
    • 0031037765 scopus 로고    scopus 로고
    • Blood pressure and vascular effects of endothelin blockade in chronic nitric oxide-deficient hypertension
    • Moreau P, Takase H, Kung CF, Shaw S, Luscher TF. Blood pressure and vascular effects of endothelin blockade in chronic nitric oxide-deficient hypertension. Hypertension. 1997;29:763-769.
    • (1997) Hypertension , vol.29 , pp. 763-769
    • Moreau, P.1    Takase, H.2    Kung, C.F.3    Shaw, S.4    Luscher, T.F.5
  • 15
    • 0029068842 scopus 로고
    • Antihypertensive effects of a novel endothelin-A receptor antagonist in rats
    • Bird JE, Moreland S, Waldron TL, Powell JR. Antihypertensive effects of a novel endothelin-A receptor antagonist in rats. Hypertension. 1995;25: 1191-1195.
    • (1995) Hypertension , vol.25 , pp. 1191-1195
    • Bird, J.E.1    Moreland, S.2    Waldron, T.L.3    Powell, J.R.4
  • 17
    • 0031941152 scopus 로고    scopus 로고
    • Prevention of the cardiovascular and renal effects of angiotensin II by endothelin blockade
    • Herizi A, Jover B, Bouriquet N, Mimran A. Prevention of the cardiovascular and renal effects of angiotensin II by endothelin blockade. Hypertension. 1998;31:10-14.
    • (1998) Hypertension , vol.31 , pp. 10-14
    • Herizi, A.1    Jover, B.2    Bouriquet, N.3    Mimran, A.4
  • 18
    • 33745399219 scopus 로고    scopus 로고
    • Effect of endothelin antagonism on blood pressure and vascular structure in renovascular hypertensive rats
    • Li JS, Knafo L, Turgeon A, Garcia R, Schiffrin EL. Effect of endothelin antagonism on blood pressure and vascular structure in renovascular hypertensive rats. Am J Physiol. 1996;271:H88-H93.
    • (1996) Am J Physiol , vol.271
    • Li, J.S.1    Knafo, L.2    Turgeon, A.3    Garcia, R.4    Schiffrin, E.L.5
  • 19
    • 0029914370 scopus 로고    scopus 로고
    • Vascular and cardiac overexpression of endothelin-1 gene in one-kidney, one clip Goldblatt hypertensive rats but only in the late phase of two-kidney one clip Goldblatt hypertension
    • Sventek P, Turgeon A, Garcia R, Schiffrin EL. Vascular and cardiac overexpression of endothelin-1 gene in one-kidney, one clip Goldblatt hypertensive rats but only in the late phase of two-kidney one clip Goldblatt hypertension. J Hypertens. 1996;14:57-64.
    • (1996) J Hypertens , vol.14 , pp. 57-64
    • Sventek, P.1    Turgeon, A.2    Garcia, R.3    Schiffrin, E.L.4
  • 20
    • 0029067175 scopus 로고
    • Role of endogenous endothelins in the renin system of normal and two-kidney, one clip rats
    • Schricker K, Scholz H, Hamann M, Clozel M, Kramer BK, Kurtz A. Role of endogenous endothelins in the renin system of normal and two-kidney, one clip rats. Hypertension. 1995;25:1025-1029.
    • (1995) Hypertension , vol.25 , pp. 1025-1029
    • Schricker, K.1    Scholz, H.2    Hamann, M.3    Clozel, M.4    Kramer, B.K.5    Kurtz, A.6
  • 24
    • 0028156774 scopus 로고
    • Endothelin-1 and angiotensin-II stimulate delayed mitogenesis in cultured rat aortic smooth muscle cells: Evidence for common signaling mechanisms
    • Weber H, Webb ML, Serafino R, Taylor DS, Moreland S, Norman J, Molloy CJ. Endothelin-1 and angiotensin-II stimulate delayed mitogenesis in cultured rat aortic smooth muscle cells: evidence for common signaling mechanisms. Mol Endocrinol. 1994;8:148-158.
    • (1994) Mol Endocrinol , vol.8 , pp. 148-158
    • Weber, H.1    Webb, M.L.2    Serafino, R.3    Taylor, D.S.4    Moreland, S.5    Norman, J.6    Molloy, C.J.7
  • 29
    • 0032031178 scopus 로고    scopus 로고
    • Changes of blood pressure and aortic strip contractile responses to ET-1 of heterozygous female transgenic rats, TGR(mRen2)27
    • Cargnelli G, Rossi GP, Pessina AC, Luciani S, Debetto P, Ganten D, Peters J, Bova S. Changes of blood pressure and aortic strip contractile responses to ET-1 of heterozygous female transgenic rats, TGR(mRen2)27. Pharmcol Res. 1998;37:207-211.
    • (1998) Pharmcol Res , vol.37 , pp. 207-211
    • Cargnelli, G.1    Rossi, G.P.2    Pessina, A.C.3    Luciani, S.4    Debetto, P.5    Ganten, D.6    Peters, J.7    Bova, S.8
  • 30
    • 0028891914 scopus 로고
    • Haemodynamic effects of losartan and the endothelin antagonist, SB 209670, in conscious, transgenic ((mRen-2)27), hypertensive rats
    • Gardiner SM, March JE, Kemp PA, Mullins JJ, Bennett T. Haemodynamic effects of losartan and the endothelin antagonist, SB 209670, in conscious, transgenic ((mRen-2)27), hypertensive rats. Br J Pharmacol. 1995;116:2237-2244.
    • (1995) Br J Pharmacol , vol.116 , pp. 2237-2244
    • Gardiner, S.M.1    March, J.E.2    Kemp, P.A.3    Mullins, J.J.4    Bennett, T.5
  • 32
    • 0017702173 scopus 로고
    • Contractile properties of small resistance vessels in spontaneously hypertensive and normotensive rats
    • Mulvany MJ, Halpern W.. Contractile properties of small resistance vessels in spontaneously hypertensive and normotensive rats. Circ Res. 1977;41:19-26.
    • (1977) Circ Res , vol.41 , pp. 19-26
    • Mulvany, M.J.1    Halpern, W.2
  • 33
    • 0018065039 scopus 로고
    • Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle cell layers
    • Mulvany MJ, Hansen PK, Aalkjaer C. Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle cell layers. Circ Res. 1978;43:854-864.
    • (1978) Circ Res , vol.43 , pp. 854-864
    • Mulvany, M.J.1    Hansen, P.K.2    Aalkjaer, C.3
  • 36
    • 0008170624 scopus 로고
    • Receptor localization with microscope
    • Yamamura HI, Enna SJ, Kuhar MJ, eds. New York, NY: Raven Press
    • Kuhar MJ. Receptor localization with microscope. In: Yamamura HI, Enna SJ, Kuhar MJ, eds. Neurotransmitter Receptor Binding. New York, NY: Raven Press; 1985:153-176.
    • (1985) Neurotransmitter Receptor Binding , pp. 153-176
    • Kuhar, M.J.1
  • 37
    • 0002751296 scopus 로고
    • A laboratory guide for the in vitro labelling of receptors in tissue sections for autoradiography
    • Van Leeuwe FW, Buijs RM, Pool CW, Pach O, eds. Amsterdam, Netherlands: Elsevier/North Holland
    • Palacios JM, Cortes R, Dietl MM. A laboratory guide for the in vitro labelling of receptors in tissue sections for autoradiography. In: Van Leeuwe FW, Buijs RM, Pool CW, Pach O, eds. Molecular Neuroanatomy. Amsterdam, Netherlands: Elsevier/North Holland; 1988:95-110.
    • (1988) Molecular Neuroanatomy , pp. 95-110
    • Palacios, J.M.1    Cortes, R.2    Dietl, M.M.3
  • 42
    • 0342356982 scopus 로고    scopus 로고
    • Systemic blockade of the ETB receptor increases peripheral vascular resistance in healthy volunteers in vivo
    • Abstract
    • Strachan FE, Spratt JC, Wilkinson IB, Webb DJ. Systemic blockade of the ETB receptor increases peripheral vascular resistance in healthy volunteers in vivo. Hypertension. 1998;32:618. Abstract.
    • (1998) Hypertension , vol.32 , pp. 618
    • Strachan, F.E.1    Spratt, J.C.2    Wilkinson, I.B.3    Webb, D.J.4
  • 44
    • 0343662227 scopus 로고    scopus 로고
    • Bosentan normalizes blood pressure, but does not prevent renal pathology in the diabetic REN-2 rat
    • Abstract
    • Wilkinson-Berka J, Kelly D, Cooper M, Skinner S. Bosentan normalizes blood pressure, but does not prevent renal pathology in the diabetic REN-2 rat. Hypertension. 1998;32:608-608. Abstract.
    • (1998) Hypertension , vol.32 , pp. 608-608
    • Wilkinson-Berka, J.1    Kelly, D.2    Cooper, M.3    Skinner, S.4
  • 46
    • 0025609784 scopus 로고
    • In vitro vascular reactivity to endothelin: A comparison between young and old normotensive and hypertensive rats
    • Cargnelli G, Rossi G, Bova S, Pessina AC. In vitro vascular reactivity to endothelin: a comparison between young and old normotensive and hypertensive rats. Clin Exp Hypertens. 1990;12:1437-1451.
    • (1990) Clin Exp Hypertens , vol.12 , pp. 1437-1451
    • Cargnelli, G.1    Rossi, G.2    Bova, S.3    Pessina, A.C.4
  • 47
    • 0026335958 scopus 로고
    • Decreased density of endothelin-1 binding sites in aortic smooth muscle cells of spontaneously hypertensive rats
    • Zanin L, Rossi GP, Pauletto P, Tonello M, Cargnelli G, Pessina AC. Decreased density of endothelin-1 binding sites in aortic smooth muscle cells of spontaneously hypertensive rats. J Hypertens. 1991;9(suppl): S190-S191.
    • (1991) J Hypertens , vol.9 , Issue.SUPPL.
    • Zanin, L.1    Rossi, G.P.2    Pauletto, P.3    Tonello, M.4    Cargnelli, G.5    Pessina, A.C.6
  • 48
    • 0025080602 scopus 로고
    • Structure and function of small arteries
    • Mulvany MJ, Aalkjaer C. Structure and function of small arteries. Physiol Rev. 1990;70:921-961.
    • (1990) Physiol Rev , vol.70 , pp. 921-961
    • Mulvany, M.J.1    Aalkjaer, C.2
  • 49
    • 0031900281 scopus 로고    scopus 로고
    • Nephroprotection of an ET(A)-receptor blocker (LU 135252) in salt-loaded uninephrectomized stroke-prone spontaneously hypertensive rats
    • Orth SR, Esslinger JP, Amann K, Schwarz U, Raschack M, Ritz E. Nephroprotection of an ET(A)-receptor blocker (LU 135252) in salt-loaded uninephrectomized stroke-prone spontaneously hypertensive rats. Hypertension. 1998;31:995-1001.
    • (1998) Hypertension , vol.31 , pp. 995-1001
    • Orth, S.R.1    Esslinger, J.P.2    Amann, K.3    Schwarz, U.4    Raschack, M.5    Ritz, E.6
  • 50
    • 0032948745 scopus 로고    scopus 로고
    • Early-onset but not late-onset endothelin-A receptor blockade can modulate hypertension, cerebral edema, and proteinuria in stroke-prone hypertensive rats
    • Blezer EL, Nicolay K, Goldschmeding R, Jansen GH, Koomans HA, Rabelink TJ, Joles JA. Early-onset but not late-onset endothelin-A receptor blockade can modulate hypertension, cerebral edema, and proteinuria in stroke-prone hypertensive rats. Hypertension. 1999;33: 137-144.
    • (1999) Hypertension , vol.33 , pp. 137-144
    • Blezer, E.L.1    Nicolay, K.2    Goldschmeding, R.3    Jansen, G.H.4    Koomans, H.A.5    Rabelink, T.J.6    Joles, J.A.7
  • 51
    • 0031767781 scopus 로고    scopus 로고
    • Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats
    • Teisman AC, Pinto YM, Buikema H, Flesch M, Bohm M, Paul M, van Gilst WH. Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats. J Hypertens. 1998;16:1759-1765.
    • (1998) J Hypertens , vol.16 , pp. 1759-1765
    • Teisman, A.C.1    Pinto, Y.M.2    Buikema, H.3    Flesch, M.4    Bohm, M.5    Paul, M.6    Van Gilst, W.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.