Differences in potency and efficacy of a series of phenylisopropylamine/phenylethylamine pairs at 5-HT2A and 5-HT2C receptors

British Journal of Pharmacology

Volumn 136, Issue 4, 2002, Pages 510-519

  Acuña Castillo, Claudio ^a   Villalobos, Claudio ^a   Moya, Pablo R ^a   Sáez, Patricio ^a   Cassels, Bruce K ^a   Huidobro Toro, J Pablo ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Hallucinogenesis; Hallucinogenic phenylalkylamines; Phenylisopropylamines phenylethylamines

Indexed keywords

2,5 DIMETHOXY 4 NITROPHENYLETHYLAMINE; 2,5-DIMETHOXY-4-NITROPHENYLETHYLAMINE; ETHYLAMINE; NITRO DERIVATIVE; PHENETHYLAMINE DERIVATIVE; PROPYLAMINE; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR; (3 CHLOROPHENYL)PIPERAZINE; 1 (2,5 DIMETHOXY 4 NITROPHENYL) 2 AMINOPROPANE; 2,5 DIMETHOXY 4 IODOPHENYLETHYLAMINE; 2,5 DIMETHOXY 4 METHYLPHENYLETHYLAMINE; 2,5 DIMETHOXY 4 PHENYLISOPROPYLAMINE; 2,5 DIMETHOXY 4 TRIFLUOROMETHYLPHENYLETHYLAMINE; 2,5 DIMETHOXYPHENYLETHYLAMINE; 4 (4 FLUOROBENZOYL) 1 (4 PHENYLBUTYL)PIPERIDINE; 4 BROMO 2,5 DIMETHOXYPHENYLETHYLAMINE; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 6 CHLORO 2 (1 PIPERAZINYL)PYRAZINE; 8 [4 (5 AMINO 2,4 DIMETHOXYBENZOYL)BUTYL] 1,3,8 TRIAZASPIRO[4.5]DECANE 2,4 DIONE; 8 [5 [2,4 DIMETHOXY 5 (4 TRIFLUOROMETHYLPHENYL)SULFONAMIDO]PHENYL 5 OXOPENTYL] 1,3,8 TRIAZASPIRO[4,5]DECANE 2,4 DIONE; ALPHA METHYLSEROTONIN; ANILINE DERIVATIVE; BROMINE; HYDROGEN; IODINE; METHYL GROUP; NITRITE; PHENYLISOPROPYLAMINE DERIVATIVE; SEROTONIN; SEROTONIN 2 AGONIST; SEROTONIN 2 ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; CHEMISTRY; DRUG EFFECT; FEMALE; IN VITRO STUDY; OOCYTE; PATCH CLAMP; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION; XENOPUS LAEVIS; ANIMAL CELL; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY;

ANIMALS; ETHYLAMINES; FEMALE; NITRO COMPOUNDS; OOCYTES; PATCH-CLAMP TECHNIQUES; PHENETHYLAMINES; PROPYLAMINES; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS; ANIMAL; IN VITRO; SUPPORT, NON-U.S. GOV'T;

EID: 0035984936     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704747     Document Type: Article

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