NAIP-ΔEx10-11: a novel splice variant of the apoptosis inhibitor NAIP differently expressed in drug-sensitive and multidrug-resistant HL60 leukemia cells

Leukemia Research

Volumn 26, Issue 9, 2002, Pages 857-862

  Notarbartolo, Monica ^a   Cervello, Melchiorre ^b   Dusonchet, Luisa ^a   D'Alessandro, Natale ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b CNR   (Italy)

Author keywords

Alternative splicing; Apoptosis; HL60 leukemia; Multidrug resistance; NAIP

Indexed keywords

APOPTOSIS INHIBITOR; NEURONAL APOPTOSIS INHIBITORY PROTEIN; UNCLASSIFIED DRUG; BIRC1 PROTEIN, HUMAN; ISOPROTEIN; NERVE PROTEIN; RNA; RNA PRECURSOR; TUMOR PROTEIN;

ALTERNATIVE RNA SPLICING; ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN VARIANT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; WESTERN BLOTTING; APOPTOSIS; BRAIN LEVEL; CELL CULTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; DRUG RESISTANCE; EXON; GENE DELETION; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ALTERNATIVE SPLICING; APOPTOSIS; BRAIN CHEMISTRY; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; EXONS; HL-60 CELLS; HUMANS; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; NEURONAL APOPTOSIS-INHIBITORY PROTEIN; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RNA PRECURSORS; RNA, NEOPLASM; SEQUENCE DELETION; TUMOR CELLS, CULTURED;

EID: 0035984439     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(02)00016-4     Document Type: Article

References (23)

1. The inhibitors of apoptosis (IAPs) and their emerging role in cancer
2. IAP family proteins-suppressors of apoptosis
3. A human IAP-family gene, apollon, expressed in human brain cancer cells
4. Livin, a novel inhibitor-of-apoptosis (IAP) family member
5. The c-IAP-1 and -2 proteins are direct inhibitors of specific caspases
6. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis
7. Anti-apoptotic gene, survivin, and prognosis of neuroblastoma
8. Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias
9. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy
10. Neuronal apoptosis inhibitory protein (NAIP)-like immunoreactivity in brains of adult patients with Down syndrome
11. Cloning and characterization of the multiple murine homologues of neuronal apoptosis inhibitory protein (NAIP)
12. Genomic sequence analysis of the mouse NAIP gene array
13. Alternative splicing and programmed cell death
14. Survivin Ex3 and survivin-2B: two novel splice variants of the apoptotic inhibitor survivin with different antiapoptotic properties
15. Three differentially expressed survivin cDNA variants encode proteins with distinct antiapoptotic functions
16. Identification of two distinct transcripts for the neuronal apoptosis inhibitory gene
17. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
18. NAIP interacts with hippocalcin and protects neurons against calcium-induced cell death through caspase-3-dependent and -independent pathways
19. The neuronal apoptosis inhibitory protein suppresses neuronal differentiation and apoptosis in PC12 cells
20. Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
21. Human ovarian cancer and cisplatin resistance: possible role of apoptosis proteins
22. Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray