Neonatal chemical sympathectomy attenuates fructose-induced hypertriglyceridemia and hypertension in rats

Chinese Journal of Physiology

Volumn 44, Issue 1, 2001, Pages 25-31

  Hsieh, Po Shiuan ^a   Huang, Wann Chu ^b  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TZU CHI UNIVERSITY   (Taiwan)

Author keywords

Chemical sympathectomy; Fructose; Guanethidine; Hyperinsulinemia; Hypertension; Hypertriglyceridemia; Sympathetic nerves

Indexed keywords

ADRENERGIC RECEPTOR STIMULATING AGENT; FRUCTOSE; INSULIN; PHENYLEPHRINE; TYRAMINE;

ADRENERGIC SYSTEM; ANIMAL; ARTICLE; BLOOD; BLOOD PRESSURE; BODY WEIGHT; CHEMICAL SYMPATHECTOMY; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GLUCOSE BLOOD LEVEL; HEART RATE; HYPERTENSION; HYPERTRIGLYCERIDEMIA; MALE; NEWBORN; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; BLOOD GLUCOSE; BLOOD PRESSURE; BODY WEIGHT; FRUCTOSE; HEART RATE; HYPERTENSION; HYPERTRIGLYCERIDEMIA; INSULIN; MALE; PHENYLEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; SYMPATHECTOMY, CHEMICAL; SYMPATHETIC NERVOUS SYSTEM; SYMPATHOMIMETICS; TYRAMINE;

EID: 0035978187     PISSN: 03044920     EISSN: 26660059     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Abe, H., Tamada, N., Kamata, K., Kuwaki, T., Shimada, M., Osuga, J., Shionoiri, F., Yahagi, N., Kadowaki, T., Tamemoto, H., Ishibashi, S., Yazaki, Y. and Makuuchi, M. Hypertension, Hypertriglyceridemia and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1. J. Clin. Invest. 101: 1784-1788, 1998.
2. Ahren, B. and Lundquist, I. Adrenalectomy and chemical sympathectomy by 6-hydroxydopamine. Effects on basal and stimulated insulin secretion. Pflugers Arch. 390: 17-21, 1981.
3. Anuradha, C. and Balakrishnan, S. Taurine attenuates hypertension and improves insulin sensitivity in the fructose-fed rat, an animal model of insulin resistance. Can. J. Physiol. Pharmacol. 77: 749-754, 1999.
4. Banos, G., Carvajal, K., Cardoso, G., Zamora, J. and Franco, M. Vascular reactivity and effect of serum in a rat model of hypertriglyceridemia and hypertension. Am. J. Hyperten. 10: 379-388, 1997.
5. Bennett, T. and Gardiner, S. Factors contributing to the mainteance of arterial blood pressure in adult rats treated neonatally with guanethidine. Clin. Exp. Hypertens. -Theory and Practice A8: 1373-1394, 1986.
6. Bianchetti, M.G., Minder, I., Beretta-Piccoli, C., Meier, A. and Weidmann, P. Effects of tyramine on blood pressure and plasma catecholamines in normal and hypertensive subjects. Klin. Wochens. 60:465-470, 1982.
7. Brands, M.W., Garrity, C.A., Holman, M.G., Keen, H.L., Alonso-Galicia, M. and Hall, J.E. High-fructose diet does not raise 24-hour mean arterial pressure in rats. Am. J. Hypertens. 7: 104-109, 1994.
8. Bunnag, P., Hori, M., Ormsby, B., Berger, M., Golub, M. and Tuck, M. Impaired in vivo adrenergic responses in diet-induced hypertensive rats. Hypertens. Res. 20: 17-21, 1997.
9. Dall'Aglio, E., Tosini, P., Ferrari, P., Zavaroni, I., Passeri, M. and Reaven, G.M. Abnormalities of insulin and lipid metabolism in Milan hypertensive rats. Am. J. Hypertens. 4: 773-775, 1991.
10. Damiano, P., Roson, M., Armando, I., Nowicki, S., Dascal, E., Cuniberti, L., Albornoz, L. and de la Riva, L. Potential role of glycerol leading to rat fructose hypertension. Hypertension 34(part 2): 1007-1011, 1999.
11. Desbuquios, B. and Aurbach, G. Use of polyethylene glycol to separate free and antibody-bound peptide hormones in the radioimmunoassays. J. Clin. Endocrinol. Metab.. 33: 732-738, 1971.
12. Finch, D., Davis, G., Bower, J. and Kirchner, K. Effect of insulin on renal sodium handling in hypertensive rats. Hypertension 15:514-518, 1990.
13. Holness, M. Hypertriglyceridemia precedes impaired muscle glucose utilization during fructose feeding. Biochem. Soc. Trans. 22: 105S, 1994.
14. Hsieh, P.S. and Huang, W.C. Chemical sympathectomy attenuates chronic hyperinsulinemia-induced hypertension in conscious rats. Nutr. Metab. Cardiovasc. Dis. 3: 173-178, 1993.
15. Hwang, I.-S., Ho, H., Hoffman, B. and Reaven, G.M. Fructose-induced insulin resistance and hypertension in rats. Hypertension 10: 512-516, 1987.
16. Hwang, I.S., Huang, W.C., Wu, J.N., Shian, L. and Reaven, G.M. Effects of fructose-induced hypertension on the renin-angiotensin-aldosterone system and arterial natriuretic factor. Am. J. Hypertens. 2: 424-427, 1989.
17. Imbach, A. Metabolic alterations following chemical sympathectomy with 6-hydroxydopamine in the rat. Recent Adv. Stud. Cardiac. Struct. Metab. 9: 259-267, 1976.
18. Iyer, S.N. and Katovich, M.J. Effect of chronic losartan potassium treatment on fructose-induced hypertension. Life Sci. 55: PL130-PL144, 1994.
19. Johnson, E., O'Brien, F. and Werbitt, R. Modification and characterization of the permanent sympathectomy produced by the administration of guanethidine to newborn rats. Eur. J. Pharmacol. 37: 45-54, 1976.
20. Juan, C.C., Fang, V.S., Hsu, Y.P., Huang, Y.J., Hsia, D.B., Yu, P. C., Kwok, C.F. and Ho, L.T. Overexpression of vascular endothelin-1 and endothelin-A receptors in a fructose-induced hypertensive rat model. J. Hypertens. 16: 1775-1782, 1998.
21. Julien, C., Kandza, P., Barres, C., Lo, M., Cerutti, C. and Sassard, J. Effects of sympathectomy on blood pressure and its variability in conscious rats. Am. J. Physiol. 259: H1337-H1342, 1990.
22. Katakam, P.V.G., Ujhelyi, M.R., Hoenig, M.E. and Miller, A.W. Endothelial dysfunction precedes hypertension in diet-induced insulin resistance. Am. J. Physiol. 275: R788-R792, 1998.
23. Kaufman, L., Peterson, M. and Smith, S. Hypertension and sympathetic hyperactivity induced in rats by high-fat or glucose diets. Am. J. Physiol. 260: E95-E100, 1991.
24. Kotchen, T.A., Zhang, H.Y., Covell, M. and Blehshmidt, N. Insulin resistance and blood pressure in Dahl rats and in one-kidney, one clip hypertensive rats. Am. J. Physiol. 261: E692-E697, 1991.
25. Landsberg, L. Role of the sympathetic adrenal system in the pathogenesis of the insulin resistance syndrome. Ann. N.Y. Acad. Sci. 892: 84-90, 1999.
26. Levin, B.E., Triscari, J., Marquet, E. and Sullivan, A.C. Dietary obesity and neonatal sympathectomy. I. Effects on body composition and brown adipose. Am. J. Physiol. 247: R979-987, 1984.
27. Martinez, F.J., Rizza, R.A. and Romero, J.C. High fructose feeding elicits insulin resistance, hyperinsulinemia, and hypertension in normal Mongrel dogs. Hypertension 23: 456-463, 1994.
28. Matsui, H., Okumura, K., Kawakami, K., Hibino, M., Toki, Y. and Ito, T. Improved insulin sensitivity by bezafibrate in rats. Relationship to fatty acid composition of skeletal-muscle triglycerides. Diabetes 46: 348-359, 1997.
29. Mondan, C.E. and Reaven, G.M. Evidence of abnormalities of insulin metabolism in rats with spontaneous hypertension. Metabolism 37: 303-305, 1988.
30. Penicaud, L., Berthault, M., Morin, J., Dubar, M., Ktorza, A. and Ferre, P. Rilmenidine normalizes fructose-induced insulin resistance and hypertension in rats. J. Hypertens. (Suppl.) 16: S45-S49, 1998.
31. Reaven, G.M. Insulin resistance, hyperinsulinemia, and hypertriglyceridemia and hypertension: parallels between human disease and rodent models. Diabetes Care 14: 195-202, 1991.
32. Reaven, G.M., Lithell, H. and Landsberg, L. Hypertension and associated metabolic abnormalities: the role of insulin resistance and the sympathoadrenal system. N. Engl. J. Med. 334: 374-381, 1996.
33. Si, X., Webb, R. and Richey, J. Bezafibrate, an anti-hypertriglyceridemic drug, attenuates vascular hyperresponsiveness and elevated blood pressure in fructose-induced hypertensive rats. Can. J. Physiol. Pharmacol. 77: 755-762, 1999.
34. Tsai, L.M. and Huang, W.C.. Vascular expression of heat shock protein 72 in fructose-induced hypertensive rats. Chin. J. Physiol. 41: 25-31, 1998.
35. Tsuruta, M., Hashimoto, R., Adachi, H., Imaizumi, T. and Nomura, G. Hyperinsulinemia as a predictor of hypertension: an 11-year follow-up study in Japan. J. Hyperten. 14: 483-488, 1996.
36. Verma, S., Bhanot. S. and McNeill, J. Sympathectomy prevents fructose-induced hyperinsulinemia and hypertension. Eur. J. Pharmacol. 373: R1-R4, 1999.
37. Waddell, M. and Fallon, H. The effect of high-carbohydrate diets on liver triglyceride formation in the rat. J. Clin. Invest. 52: 2725-2731, 1982.
38. Wahlfeld, A. Triglyceride: determination after enzymatic hydrolysis. In: Methods of enzymatic analysis, edited by Bergmeyer, H., Academic Press, New York, 1974; vol. 4, pp. 1831-1835.
39. Young, J.B. Effect of experimental hyperinsulinemia on sympathetic nervous system activity in the rat. Life Sci. 43: 193-200, 1988.
40. Zavaroni, I., Chen, Y. and Reaven, G.M. Studies of the mechanism of fructose-induced hypertriglyceridemia in the rat. Metabolism 31: 1077-1083, 1982.