A Conserved Subtilisin-like Protein TgSUB1 in Microneme Organelles of Toxoplasma gondii

Journal of Biological Chemistry

Volumn 276, Issue 48, 2001, Pages 45341-45348

  Miller, Steven A ^a   Binder, Emily M ^a   Blackman, Michael J ^b   Carruthers, Vern B ^c   Kim, Kami ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CLONING; ENZYME INHIBITION; GENES; PROTEINS;

GENE ENCODING;

BIOCHEMISTRY;

BACTERIAL PROTEIN; BREFELDIN A; PROTEIN TGSUB1; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; SUBTILISIN; UNCLASSIFIED DRUG; ENZYME INHIBITOR; FUNGAL PROTEIN; SUB1 PROTEIN; SUB1 PROTEIN, TOXOPLASMA GONDII; TRANSCRIPTION FACTOR;

APICOMPLEXA; ARTICLE; CELL INVASION; GENE; GENETIC CODE; HOST CELL; HOST PARASITE INTERACTION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN SECRETION; TBSUB1 GENE; TOXOPLASMA GONDII; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; CHEMISTRY; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; EXPRESSED SEQUENCE TAG; IMMUNOELECTRON MICROSCOPY; METABOLISM; MICROSOME; MOLECULAR GENETICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; SEQUENCE HOMOLOGY; SERODIAGNOSIS; TIME; TOXOPLASMA; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

APICOMPLEXA; BACTERIA (MICROORGANISMS); PROTOZOA; TOXOPLASMA GONDII;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; BLOTTING, WESTERN; BREFELDIN A; CATALYTIC DOMAIN; CLONING, MOLECULAR; CONSERVED SEQUENCE; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; EXPRESSED SEQUENCE TAGS; FUNGAL PROTEINS; MICROSCOPY, ELECTRON; MICROSCOPY, IMMUNOELECTRON; MICROSOMES; MOLECULAR SEQUENCE DATA; PRECIPITIN TESTS; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; SUBTILISINS; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS; TOXOPLASMA; TRANSCRIPTION FACTORS;

EID: 0035976961     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M106665200     Document Type: Article

References (41)

1. Boothroyd, J. C., Black, M., Bonnefoy, S., Hehl, A., Knoll, L. J., Manger, I. D., Ortega-Barria, E., and Tomavo, S. (1997) Philos. Trans. R. Soc. Lond-Biol. Sci. 352, 1347-1354
2. Carruthers, V. B., and Sibley, L. D. (1997) Eur. J. Cell Biol. 73, 114-123
3. Dobrowolski, J. M., Carruthers, V. B., and Sibley, L. D. (1997) Mol. Microbiol. 26, 163-173
4. Conseil, V., Soete, M., and Dubremetz, J. F. (1999) Antimicrob. Agents Chemother. 43, 1358-1361
5. Breton, C. B., Blisnick, T., Jouin, H., Barale, J. C., Rabilloud, T., Langsley, G., and Pereira da Silva, L. H. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 9647-9651
6. Mayer, R., Picard, I., Lawton, P., Grellier, P., Barrault, C., Monsigny, M., and Schrevel, J. (1991) J. Med. Chem. 34, 3029-3035
7. Olaya, P., and Wasserman, M. (1991) Biochim. Biophys. Acta 1096, 217-221
8. Dejkriengkraikhul, P., and Wilairat, P. (1983) Z. Parasitenkd. 69, 313-317
9. Banyal, H. S., Misra, G. C., Gupta, C. M., and Dutta, G. P. (1981) J. Parasitol. 67, 623-626
10. Blackman, M. J., Heidrich, H. G., Donachie, S., McBride, J. S., and Holder, A. A. (1990) J. Exp. Med. 172, 379-382
11. Blackman, M. J., Fujioka, H., Stafford, W. H., Sajid, M., Clough, B., Fleck, S. L., Aikawa, M., Grainger, M., and Hackett, F. (1998) J. Biol. Chem. 273, 23398-23409
12. Barale, J. C., Blisnick, T., Fujioka, H., Alzari, P. M., Aikawa, M., Braun-Breton, C., and Langsley, G. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 6445-6450
13. Hackett, F., Sajid, M., Withers-Martinez, C., Grainger, M., and Blackman, M. J. (1999) Mol. Biochem. Parasitol. 103, 183-195
14. Sajid, M., Withers-Martinez, C., and Blackman, M. J. (2000) J. Biol. Chem. 275, 631-641
15. Louie, K., and Conrad, P. A. (1999) Mol. Biochem. Parasitol. 103, 211-223
16. Garcia-Reguet, N., Lebrun, M., Fourmaux, M. N., Mercereau-Puijalon, O., Mann, T., Beckers, C. J., Samyn, B., Van Beeumen, J., Bout, D., and Dubremetz, J. F. (2000) Cell Microbiol. 2, 353-364
17. Brydges, S. D., Sherman, G. D., Nockemann, S., Loyens, A., Daubener, W., Dubremetz, J., and Carruthers, V. B. (2000) Mol. Biochem. Parasitol. 111, 51-66
18. Rabenau, K. E., Sohrabi, A., Tripathy, A., Reitter, C., Ajioka, J. W., Tomley, F. M., and Carruthers, V. B. (2001) Mol. Microbiol. 41, 537-547
19. Soldati, D., Lassen, A., Dubremetz, J. F., and Boothroyd, J. C. (1998) Mol. Biochem. Parasitol. 96, 37-48
20. Sadak, A., Taghy, Z., Fortier, B., and Dubremetz, J. F. (1988) Mol. Biochem. Parasitol. 29, 203-211
21. Hehl, A. B., Lekutis, C., Grigg, M. E., Bradley, P. J., Dubremetz, J. F., Ortega-Barria, E., and Boothroyd, J. C. (2000) Infect. Immun. 68, 7078-7086
22. Donahue, C. G., Carruthers, V. B., Gilk, S. D., and Ward, G. E. (2000) Mol. Biochem. Parasitol. 111, 15-30
23. Brecht, S., Carruthers, V. B., Ferguson, D. J., Giddings, O. K., Wang, G., Jaekle, U., Harper, J. M., Sibley, L. D., and Soldati, D. (2000) J. Biol. Chem. 26, 4119-4127
24. Carruthers, V. B., Sherman, G. D., and Sibley, L. D. (2000) J. Biol. Chem. 275, 14346-14353
25. Kocken, C. H., Narum, D. L., Massougbodji, A., Ayivi, B., Dubbeld, M. A., van der Wel, A., Conway, D. J., Sanni, A., and Thomas, A. W. (2000) Mol. Biochem. Parasitol. 109, 147-156
26. Carruthers, V. B., Giddings, O. K., and Sibley, L. D. (1999) Cell. Microbiol. 1, 225-235
27. Reiss, M., Viebig, N., Brecht, S., Fourmaux, M. N., Soete, M., Di Cristina, M., Dubremetz, J. F., and Soldati, D. (2001) J. Cell Biol. 152, 563-578
28. Qin, C. L., Tang, J., and Kim, K. (1998) Mol. Biochem. Parasitol. 93, 273-283
29. Wan, K. L., Carruthers, V. B., Sibley, L. D., and Ajioka, J. W. (1997) Mol. Biochem. Parasitol. 84, 203-214
30. Siezen, R. J., and Leunissen, J. A. (1997) Protein Sci. 6, 501-523
31. Eisenhaber, B., Bork, P., and Eisenhaber, F. (1998) Protein Eng. 11, 1155-1161
32. Siezen, R. J., de Vos, W. M., Leunissen, J. A., and Dijkstra, B. W. (1991) Protein Eng. 4, 719-737
33. Carruthers, V. B., and Sibley, L. D. (1999) Mol. Microbiol. 31, 421-428
34. Lippincott-Schwartz, J., Yuan, L. C., Bonifacino, J. S., and Klausner, R. D. (1989) Cell 56, 801-813
35. Saraste, J., and Kuismanen, E. (1984) Cell 38, 535-549
36. Ossorio, P. N., Schwartzman, J. D., and Boothroyd, J. C. (1992) Mol. Biochem. Parasitol. 50, 1-15
37. Brown, P. J., Billington, K. J., Bumstead, J. M., Clark, J. D., and Tomley, F. M. (2000) Mol. Biochem. Parasitol. 107, 91-102
38. Fourmaux, M. N., Achbarou, A., Mercereau-Puijalon, O., Biderre, C., Briche, I., Loyens, A., Odberg-Ferragut, C., Camus, D., and Dubremetz, J. F. (1996) Mol. Biochem. Parasitol. 83, 201-210
39. Howell, S. A., Withers-Martinez, C., Kocken, C. H. M., Thomas, A. W. and Blackman, M. J. (2001) J. Biol. Chem. 276, 31311-31320
40. Suss-Toby, E., Zimmerberg, J., and Ward, G. E. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8413-8418
41. Pacheco-Soares, C., and De Souza, W. (1998) Cell Struct. Funct. 23, 159-168