TgM2AP participates in toxoplasma gondii invasion of host cells and is tightly associated with the adhesive protein TgMIC2

Molecular Microbiology

Volumn 41, Issue 3, 2001, Pages 537-547

  Rabenau, Karen E ^a   Sohrabi, Afshin ^a   Tripathy, Ashutosh ^b   Reitter, Christopher ^c   Ajioka, James W ^c   Tomley, Fiona M ^d   Carruthers, Vern B ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANE PROTEIN; PROTEIN TGMIC2; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL INVASION; CONTROLLED STUDY; EIMERIA TENELLA; FIBROBLAST; GOLGI COMPLEX; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; NEOSPORA CANINUM; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PARASITE VIRULENCE; PRIORITY JOURNAL; PROTEIN PROCESSING; TOXOPLASMA GONDII;

AMINO ACID SEQUENCE; ANIMALS; CIRCULAR DICHROISM; CLONING, MOLECULAR; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTOZOAN PROTEINS; SECRETORY VESICLES; SEQUENCE ALIGNMENT; TOXOPLASMA; TOXOPLASMOSIS;

EID: 0034883267     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2001.02513.x     Document Type: Article

References (33)

1. Characterization of microneme proteins of Toxoplasma gondii
2. The toxoplasma micronemal protein, M.I.C 4 is an adhesin composed of six conserved apple domains
3. Molecular characterization of TgMIC5, a proteolytically processed antigen secreted from the micronemes of Toxoplasma gondii
4. Induction of secretion and surface capping of microneme proteins in Eimeria tenella
5. Secretion of micronemal proteins is associated with Toxoplasma invasion of host cells
6. Ethanol and acetaldehyde elevate intracellular calcium and stimulate microneme discharge in Toxoplasma gondii
7. The Toxoplasma adhesive protein MIC2 is proteolytically processed at multiple sites by two parasite-derived proteases
8. Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts
9. Serine protease inhibitors block invasion of host cells by Toxoplasma gondii
10. Two conserved amino acid motifs mediate protein targeting to the micronemes of the apicomplexan parasite Toxoplasma gondii
11. Participation of myosin in gliding motility and host cell invasion by Toxoplasma gondii
12. Toxoplasma invasion of mammalian cells is powered by the actin cytoskeleton of the parasite
13. Effects of extracellular potassium on acid release and motility initiation in Toxoplasma gondii
14. The MIC1 microneme protein of Toxoplasma gondii contains a duplicate receptor-like domain and binds to host cell surface
15. The microneme protein MIC3 of Toxoplasma gondii is a secretory adhesin that binds to both the surface of the host cells and the surface of the parasite
16. Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins
17. Toxoplasma gondii: Molecular cloning and characterization of a novel, 18-k., Da secretory antigen, TgM.I.C. 10
18. Conservation of a gliding motility and cell invasion machinery in Apicomplexan parasites
19. A simple method for displaying the hydropathic character of a protein
20. Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin A suggests an ER recycling pathway
21. Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER
22. Molecular characterization of a thrombospondin-related anonymous protein homologue in Neospora caninum
23. Rapid and reliable fluorescent cycle sequencing of double stranded templates
24. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
25. Actomyosin motor in the merozoite of the malaria parasite, Plasmodium falciparum: Implications for red cell invasion
26. Characterization of a family of rhoptry proteins of Toxoplasma gondii
27. Processing of Toxoplasma ROP1 protein in nascent rhoptries
28. TRAP is necessary for gliding motility and infectivity of plasmodium sporozoites
29. Phylogeny of the tissue cyst-forming coccidia
30. Mix and match modules: Structure and function of micronemes from apicomplexan parasites
31. Molecular cloning and characterization of a novel acidic microneme protein (Etmic-2) from the apicomplexan protozoan parasite, Eimeria tenella
32. Toxoplasma gondii expressed sequence tags: Insight into tachyzoite gene expression
33. Molecular characterization of an expressed sequence tag locus of Toxoplasma gondii encoding the micronemal protein MIC2