Differential regulation of macrophage CCAAT-enhancer binding protein isoforms by lipopolysaccharide and cytokines

Cytokine

Volumn 12, Issue 9, 2000, Pages 1430-1436

  Tengku Muhammad, Tengku S ^a   Hughes, Timothy R ^a   Ranki, Harri ^a   Cryer, Anthony ^a   Ramji, Dipak P ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

CCAAT enhancer binding protein; Cytokines; Gene expression; J774.2 cell line; Lipopolysaccharide

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CYTOKINE; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ARTICLE; DIMERIZATION; DNA BINDING; GENE EXPRESSION REGULATION; GENETIC REGULATION; MACROPHAGE ACTIVATION; MEDIATOR RELEASE; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALIA; MURINAE;

EID: 0033802516     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2000.0711     Document Type: Article

References (15)

1. Biological role of the CCAAT enhancer binding protein family of transcription factors
2. The role of C/EBP isoforms in the control of inflammatory and native immunity functions
3. C/EBP-related protein 2 confers lipopolysaccharide-inducible expression of interleukin 6 and monocyte chemoattractant protein 1 to a lymphoblastic cell line
4. Redundancy of C/EBPα, -β, and -δ in supporting the lipopolysaccharide-induced transcription of IL-6 and monocyte chemoattractant protein-1
5. Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6
6. The NF-M transcription factor is related to C/EBPβ and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells
7. Transcription of a minimal promoter from the NF-IL6 gene is regulated by CREB/ATF and SP1 proteins in U937 promonocytic cells
8. Expression of the genes encoding CCAAT-enhancer binding protein isoforms in the mouse mammary gland during lactation and involution
9. The two C/EBP isoforms, IL-6DBP/NF-IL6 and C/EBPδ/NF-IL6β, are induced by IL-6 to promote acute-phase gene transcription via different mechanisms
10. IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP
11. Tumor necrosis factor α promotes nuclear localization of cytokine-inducible CCAAT/enhancer binding protein isoforms in hepatocytes
12. Differential regulation of lipoprotein lipase in the macrophage J774.2 cell line by cytokines
13. Synergism between interferon-γ and tumour necrosis factor-α in the regulation of lipoprotein lipase in the macrophage J774.2 cell line