Foot-and-mouth disease virus lacking the VP1 G-H loop: The mutant spectrum uncovers interactions among antigenic sites for fitness gain

Virology

Volumn 288, Issue 2, 2001, Pages 192-202

  Baranowski, Eric ^a   Ruiz Jarabo, Carmen M ^a   Lim, Filip ^a   Domingo, Esteban ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Antigenic site; Fitness; Foot and mouth disease virus; Viral quasispecies; Virus evolution; Virus receptor

Indexed keywords

ANTIGEN; ARGINYLGLYCYLASPARTIC ACID; CAPSID PROTEIN; INTEGRIN RECEPTOR; NEUTRALIZING ANTIBODY;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHIMERA; CLONE; DNA MODIFICATION; FOOT AND MOUTH DISEASE VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; VIROGENESIS; VIRUS INFECTIVITY; VIRUS MUTANT;

EID: 0035975646     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2001.1096     Document Type: Article

References (79)

1. The three-dimensional structure of foot-and-mouth disease virus at 2.9 Å resolution
2. Molecular intermediates of fitness gain of an RNA virus: Characterization of a mutant spectrum by biological and molecular cloning
3. Binary ethylenimine as an inactivant for foot-and-mouth disease virus and its application for vaccine production
4. Evidence for co-evolution of foot-and-mouth disease virus antigenicity and receptor usage
5. Evolution of cell recognition by viruses
6. Cell recognition by foot-and-mouth disease virus that lacks the RGD integrin-binding motif: Flexibility in aphthovirus receptor usage
7. Multiple virulence determinants of foot-and-mouth disease virus in cell culture
8. Developments in foot-and-mouth disease vaccines
9. Analysis of neutralizing antigenic sites on the surface of type A12 foot-and-mouth disease virus
10. Subtyping of European foot-and-mouth disease virus strains by nucleotide sequence determination
11. 3) inhibit binding and infection of foot-and-mouth disease virus to cultured cells
12. Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence
13. Antibody recognition and neutralization of foot-and-mouth disease virus
14. Long-term, large-population passage of aphthovirus can generate and amplify defective noninterfering particles deleted in the leader protease gene
15. Selection of antigenic variants of foot-and-mouth disease virus in the absence of antibodies, as revealed by an in situ assay
16. Protection of cattle against foot-and-mouth disease by a synthetic peptide
17. Foot-and-mouth disease virus populations are quasispecies
18. Rapid fitness losses in mammalian RNA virus clones due to Muller's ratchet
19. Genetic lesions associated with Muller's ratchet in an RNA virus
20. Multiple molecular pathways for fitness recovery of an RNA virus debilitated by operation of Muller's ratchet
21. Cell receptors for picornaviruses as determinants of cell tropism and pathogenesis
22. The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies
23. Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus
24. Quasispecies in viral persistence and pathogenesis of hepatitis C virus
25. The cell attachment site on foot-and-mouth disease virus includes the amino acid sequence RGD (arginine-glycine-aspartic acid)
26. The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex
27. Structure of the complex of an Fab fragment of a neutralizing antibody with foot-and-mouth disease virus: Positioning of a highly mobile antigenic loop
28. Differential restrictions on antigenic variation among antigenic sites of foot-and-mouth disease virus in the absence of antibody selection
29. Quantitation of relative fitness and great adaptability of clonal populations of RNA viruses
30. 1: Influence of the leucine residue within the RGDL motif on selectivity of integrin binding
31. Efficient infection of cells in culture by type O foot-and-mouth disease virus requires binding to cell surface heparan sulfate
32. 3 in vitro
33. 6 is a receptor for foot-and-mouth disease virus
34. Sequence analysis of monoclonal antibody resistant mutants of type O foot and mouth disease virus: Evidence for the involvement of the three surface exposed capsid proteins in four antigenic sites
35. Outbreak of foot-and-mouth disease virus serotype O in the UK caused by a pandemic strain
36. Amino acid changes outside the G-H loop of capsid protein VP1 of type O foot-and-mouth disease virus confer resistance to neutralization by antipeptide G-H serum
37. The structure and antigenicity of a type C foot-and-mouth disease virus
38. Point mutations within the betaG-betaH loop of foot-and-mouth disease virus O1K affect virus attachment to target cells
39. Structure of a major immunogenic site on foot-and-mouth disease virus
40. Evolution subverting essentiality: Dispensability of the cell attachment Arg-Gly-Asp motif in multiply passaged foot-and-mouth disease virus
41. RGD sequence of foot-and-mouth disease virus is essential for infecting cells via the natural receptor but can be bypassed by an antibody-dependent enhancement pathway
42. Antibody recognition of picornaviruses and escape from neutralization: A structural view
43. Antibodies raised in a natural host and monoclonal antibodies recognize similar antigenic features of foot-and-mouth disease virus
44. Direct evaluation of the immunodominance of a major antigenic site of foot-and-mouth disease virus in a natural host
45. Extensive antigenic heterogeneity of foot-and-mouth disease virus of serotype C
46. Antigenic heterogeneity of a foot-and-mouth disease virus serotype in the field is mediated by very limited sequence variation at several antigenic sites
47. A single amino acid substitution affects multiple overlapping epitopes in the major antigenic site of foot-and-mouth disease virus of serotype C
48. Implications of a quasispecies genome structure: Effect of frequent, naturally occurring amino acid substitutions on the antigenicity of foot-and-mouth disease virus
49. Reactivity with monoclonal antibodies of viruses from an episode of foot-and-mouth disease
50. Systematic replacement of amino acid residues within an Arg-Gly-Asp-containing loop of foot-and-mouth disease virus and effect on cell recognition
51. 3 as its receptor
52. A single amino acid substitution in nonstructural protein 3A can mediate adaptation of foot-and-mouth disease virus to the guinea pig
53. A multiply substituted G-H loop from foot-and-mouth disease virus in complex with a neutralizing antibody: A role for water molecules
54. Structural and serological evidence for a novel mechanism of antigenic variation in foot-and-mouth disease virus
55. Interferon resistance of hepatitis C virus genotype 1b: Relationship to nonstructural 5A gene quasispecies mutations
56. Antibodies against a preselected peptide recognize and neutralize foot and mouth disease virus
57. A calcium-dependent antibody for identification and purification of recombinant proteins
58. Evolution of mouse hepatitis virus: Detection and characterization of spike deletion variants during persistent infection
59. Memory in viral quasispecies
60. Antigenic properties and population stability of a foot-and-mouth disease virus with an altered Arg-Gly-Asp receptor-recognition motif
61. Tissue culture adaptation of foot-and-mouth disease virus selects viruses that bind to heparin and are attenuated in cattle
62. Cellular receptors for viruses: Links to tropism and pathogenesis
63. Differentiation of convalescent animals from those vaccinated against foot-and-mouth disease by a peptide ELISA
64. Multiple genetic variants arise in the course of replication of foot-and-mouth disease virus in cell culture
65. Foot-and-mouth disease in Europe
66. Foot-and-mouth disease virus: A long known virus, but a current threat
67. DNA shuffling by random fragmentation and reassembly: In vitro recombination for molecular evolution
68. Recent structural solutions for antibody neutralization of viruses
69. Location and characterization of the antigenic portion of the FMDV immunizing protein
70. A large-scale evaluation of peptide vaccines against foot-and-mouth disease: Lack of solid protection in cattle and isolation of escape mutants
71. Genomic nucleotide sequence of a foot-and-mouth disease virus clone and its persistent derivatives. Implications for the evolution of viral quasispecies during a persistent infection
72. Efficient neutralization of foot-and-mouth disease virus by monovalent antibody binding
73. Structure of the major antigenic loop of foot-and-mouth disease virus complexed with a neutralizing antibody: Direct involvement of the Arg-Gly-Asp motif in the interaction
74. Induced pocket to accommodate the cell attachment Arg-Gly-Asp motif in a neutralizing antibody against foot-and-mouth-disease virus
75. Flexibility of the major antigenic loop of foot-and-mouth disease virus bound to a Fab fragment of a neutralising antibody: Structure and neutralisation
76. A similar pattern of interaction for different antibodies with a major antigenic site of foot-and-mouth disease virus: Implications for intratypic antigenic variation
77. Infectious foot-and-mouth disease virus derived from a cloned full-length cDNA