Antigenic properties and population stability of a foot-and-mouth disease virus with an altered Arg-Gly-Asp receptor-recognition motif

Journal of General Virology

Volumn 80, Issue 8, 1999, Pages 1899-1909

  Ruiz Jarabo, Carmen M ^a   Sevilla, Noemí ^a,b   Dávila, Mercedes ^a   Gómez Mariano, Gema ^a   Baranowski, Eric ^a   Domingo, Esteban ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; VIRUS ANTIGEN; VIRUS RECEPTOR;

ANIMAL CELL; ANTIGENICITY; ARTICLE; CELL STRAIN BHK; ENZYME LINKED IMMUNOSORBENT ASSAY; FOOT AND MOUTH DISEASE VIRUS; GENETIC STABILITY; NONHUMAN; PRIORITY JOURNAL; REVERTANT; VIRUS NEUTRALIZATION; WESTERN BLOTTING;

ANIMALIA; CAVIA; FOOT-AND-MOUTH DISEASE VIRUS; MIRIDAE; RNA VIRUSES; SUS SCROFA;

EID: 0032794285     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-80-8-1899     Document Type: Article

References (64)

1. Acharya, R., Fry, E., Stuart, D., Fox, G., Rowlands, D. J. & Brown, F. (1989). The three dimensional structure of foot-and-mouth disease virus at 2·9 Å resolution. Nature 337, 709-716.
2. Bachrach, H. L. (1968). Foot-and-mouth disease virus. Annual Review of Microbiology 22, 201-244.
3. Baranowski, E., Sevilla, N., Verdaguer, N., Ruiz-Jarabo, C. M., Beck, E. & Domingo, E. (1998). Multiple virulence determinants of foot-and-mouth disease virus in cell culture. Journal of Virology 72, 6362-6372.
4. 3) inhibit binding and infection of foot-and-mouth disease virus to cultured cells. Journal of Virology 69, 2664-2666.
5. Bittle, J. L., Houghten, R. A., Alexander, H., Shinnick, T. M., Sutcliffe, J. G., Lerner, R. A., Rowlands, D. J. & Brown, F. (1982). Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence. Nature 298, 30-33.
6. Borrego, B. (1993). Respuesta inmune frente a distintos antígenos del virus de la fiebre aftosa. Variantes virales obtenidas en presencia o ausenda de selectión par anticuerpos específicos. PhD thesis, Universidad Autónoma de Madrid, Spain.
7. Borrego, B., Novella, I. S., Giralt, E., Andreu, D. & Domingo, E. (1993). Distinct repertoire of antigenic variants of foot-and-mouth disease virus in the presence or absence of immune selection. Journal of Virology 67, 6071-6079.
8. Brown, F. (1994). Foot and mouth disease. In Synthetic Vaccines, pp. 416-432. Edited by B. H. Nicholson. Oxford: Blackwell Scientific Publications.
9. Carrillo, C., Plana, J., Mascarella, R., Bergadá, J. & Sobrino, F. (1990). Genetic and phenotypic variability during replication of foot-and-mouth disease virus in swine. Virology 179, 890-892.
10. Carrillo, C., Borca, M., Moore, D. M., Morgan, D. O. & Sobrino, F. (1998). In vivo analysis of the stability and fitness of variants recovered from foot-and-mouth disease virus quasispecies. Journal of General Virology 79, 1699-1706.
11. Clarke, B. E., Carroll, A. R., Rowlands, D. J., Nicholson, B. H., Hough ten, R. A., Lerner, R. A. & Brown, F. (1983). Synthetic peptides mimic subtype specificity of foot-and-mouth disease virus. FEBS Letters 157, 261-264.
12. de la Torre, J. C., Dávila, M., Sobrino, F., Ortín, J. & Domingo, E. (1985). Establishment of cell lines persistently infected with foot-and-mouth disease virus. Virology 145, 24-35.
13. de la Torre, J. C., Martínez-Salas, E., Díez, J., Villaverde, A., Gebauer, F., Rocha, E., Dávila, M. & Domingo, E. (1988). Coevolution of cells and viruses in a persistent infection of foot-and-mouth disease virus in cell culture. Journal of Virology 62, 2050-2058.
14. Díez, J., Mateu, M. G. & Domingo, E. (1989). Selection of antigenic variants of foot-and-mouth disease virus in the absence of antibodies, as revealed by an in situ assay. Journal of General Virology 70, 3281-3289.
15. Díez, J., Dávila, M., Escarmís, C., Mateu, M. G., Domínguez, J., Pérez, J. J., Giralt, E., Melero, J. A. & Domingo, E. (1990). Unique amino acid substitutions in the capsid proteins of foot-and-mouth disease virus from a persistent infection in cell culture. Journal of Virology 64, 5519-5528.
16. Domingo, E., Dávila, M. & Ortín J. (1980). Nucleotide sequence heterogeneity of the RNA from a natural population of foot-and-mouth disease virus. Gene 11, 333-346.
17. Domingo, E., Mateu, M. G., Martínez, M. A., Dopazo, J., Moya, A. & Sobrino, F. (1990). Genetic variability and antigenic diversity of foot-and-mouth disease virus. In Applied Virology Research, vol. II, Virus Variation and Epidemiology, pp. 233-266. Edited by E. Kurstak, R. G. Marusyk, S. A. Murphy & M. H. V. Van Regenmortel. New York: Plenum Publishing.
18. Domingo, E., Escarmís, C., Martínez, M. A., Martínez-Salas, E. & Mateu, M. G. (1992). Foot-and-mouth disease virus populations are quasispecies. Current Topics in Microbiology and Immunology 176, 33-47.
19. Domingo, E. & Holland, J. J. (1994). Mutation rates and rapid evolution of RNA viruses. In Evolutionary Biology of Viruses, pp. 161-184. Edited by S. S. Morse. New York: Raven Press.
20. Escarmís, C., Dávila, M., Charpentier, N., Bracho, A., Moya, A. & Domingo, E. (1996). Genetic lesions associated with Muller's ratchet in an RNA virus. Journal of Molecular Biology 264, 255-267.
21. Escarmís, C., Carrillo, E. C., Ferrer, M., García Arriaza, J. F., López, N., Tami, C., Verdaguer, N., Domingo, E. & Franze-Fernández, M. T. (1998). Rapid selection in modified BHK-21 cells of a foot-and-mouth disease virus variant showing alterations in cell tropism. Journal of Virology 72, 10171-10179.
22. Escarmís, C. Dávila, M. & Domingo, E. (1999). Multiple molecular pathways for fitness recovery of an RNA virus debilitated by operation of Muller's ratchet. Journal of Molecular Biology 285, 495-505.
23. Fox, G., Parry, N., Barnett, P. V., McGinn, B., Rowlands, D. J. & Brown, F. (1989). The cell attachment site on foot-and-mouth disease virus includes the amino acid sequence RGD (arginine-glycine-aspartic acid). Journal of General Virology 70, 625-637.
24. Gebauer, F., de la Torre, J. C., Gomes, I., Mateu, M. G., Barahona, H., Tiraboschi, B., Bergmann, I., Auge de Mello, M. G. & Domingo, E. (1988). Rapid selection of genetic and antigenic variants of foot-and-mouth disease virus during persistence in cattle. Journal of Virology 62, 2041-2049.
25. Hernández, J., Martínez, M. A., Rocha, E., Domingo, E. & Mateu, M. G. (1992). Generation of a subtype-specific neutralization epitope in foot-and-mouth disease virus of a different subtype. Journal of General Virology 73, 213-216.
26. Hernández, J., Valero, M. L., Andreu, D., Domingo, E. & Mateu, M. G. (1996). Antibody and host cell recognition of foot-and-mouth disease virus (serotype C) cleaved at the Arg-Gly-Asp (RGD) motif: a structural interpretation. Journal of General Virology 77, 257-264.
27. Holguín, A., Hernández, J., Martínez, M. A., Mateu, M. G. & Domingo, E. (1997). Differential restrictions on antigenic variation among antigenic sites of foot-and-mouth disease virus in the absence of antibody selection. Journal of General Virology 78, 601-609.
28. Jackson, T., Ellard, F. M., Abu Ghazaleh, R., Brookes, S. M., Blackemore, W. E., Corteyn, A. H., Stuart, D. I., Newmann, J. W. I. & King, A. M. Q. (1996). Efficient infection of cells in culture by type O foot-and-mouth disease virus requires binding to cell surface heparan sulfate. Journal of Virology 70, 5282-5287.
29. 3 in vitro. Journal of Virology 71, 8357-8361.
30. Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
31. Lea, S., Hernández, J., Blakemore, W., Brocchi, E., Curry, S., Domingo, E., Fry, E., Abu Ghazaleh, R., King, A., Newman, J., Stuart, D. & Mateu, M. G. (1994). The structure and antigenicity of a type C foot-and-mouth disease virus. Structure 2, 123-139.
32. 1K affect virus attachment to target cells. Journal of Virology 71, 1046-1051.
33. Logan, D., Abu-Ghazaleh, R., Blakemore, W., Curry, S., Jackson, T., King, A., Lea, S., Lewis, R., Newman, J., Parry, N., Rowlands, D. J., Stuart, D. & Fry, E. (1993). Structure of a major immunogenic site of foot-and-mouth disease virus. Nature 362, 566-568.
34. Marilat, V., Auge de Mello, P., Tiraboschi, B., Beck, E., Gomes, I. & Bergmann, I. E. (1994). Genetic variation of foot-and-mouth disease virus during persistent infection in cattle. Virus Research 34, 31-48.
35. Martínez, M. A., Hernández, J., Piccone, M. E., Palma, E. L., Domingo, E., Knowles, N. & Mateu, M. G. (1991). Two mechanisms of antigenic diversification of foot-and-mouth disease virus. Virology 184, 695-706.
36. Martínez, M. A., Verdaguer, N., Mateu, M. G. & Domingo, E. (1997). Evolution subverting essentiality: dispensability of the cell attachment Arg-Gly-Asp motif in multiply passaged foot-and-mouth disease virus. Proceedings of the National Academy of Sciences, USA 94, 6798-6802.
37. Mason, P. W., Rieder, E. & Baxt, B. (1994). RGD sequence of foot-and-mouth disease virus is essential for infecting cells via the natural receptor but can be bypassed by an antibody-dependent enhancement pathway. Proceedings of the National Academy of Sciences, USA 91, 1932-1936.
38. Mateu, M. G. (1995). Antibody recognition of picornaviruses and escape from neutralization: a structural view. Virus Research 38, 1-24.
39. Mateu, M. G., Rocha, E., Vicente, O., Vayreda, F., Navalpotro, C., Andreu, D., Pedroso, E., Giralt, E., Enjuanes, L. & Domingo, E. (1987). Reactivity with monoclonal antibodies of viruses from an episode of foot-and-mouth disease. Virus Research 8, 261-274.
40. Mateu, M. G., Da Silva, J. L., Rocha, E., De Brum, D. L., Alonso, A., Enjuanes, L., Domingo, E. & Barahona, H. (1988). Extensive antigenic heterogeneity of foot-and-mouth disease virus of serotype C. Virology 166, 113-124.
41. Mateu, M. G., Martínez, M. A., Rocha, E., Andreu, D., Parejo, J., Giralt, E., Sobrino, F. & Domingo, E. (1989). Implications of a quasispecies genome structure: affect of frequent, naturally occurring amino acid substitutions on the antigenicity of foot-and-mouth disease virus. Proceedings of the National Academy of Sciences, USA 86, 5883-5887.
42. Mateu, M. G., Martínez, M. A., Capucci, L., Andreu, D., Giralt, E., Sobrino, F., Brocchi, E. & Domingo, E. (1990). A single amino acid substitution affects multiple overlapping epitopes in the major antigenic site of foot-and-mouth disease virus of serotype C. Journal of General Virology 71, 629-637.
43. Mateu, M. G., Hernández, J., Martínez, M. A., Feigelstock, D., Lea, S., Pérez, J. J., Giralt, E., Stuart, D., Palma, E. L. & Domingo, E. (1994). Antigenic heterogeneity of a foot-and-mouth disease virus serotype in the field is mediated by very limited sequence variation at several antigenic sites. Journal of Virology 68, 1407-1417.
44. Mateu, M. G., Andreu, D. & Domingo, E. (1995a). Antibodies raised in a natural host and monoclonal antibodies recognize similar antigenic features of foot-and-mouth disease virus. Virology 210, 120-127.
45. Mateu, M. G., Camarero, J. A., Giralt, E., Andreu, D. & Domingo, E. (1995b). Direct evaluation of the immunodominance of a major antigenic site of foot-and-mouth disease virus in a natural host. Virology 206, 298-306.
46. Mateu, M. G., Valero, M. L., Andreu, D. & Domingo, E. (1996). Systematic replacement of amino acid residues within an Arg-Gly-Asp-containing loop of foot-and-mouth disease virus: effect on cell recognition. Journal of Biological Chemistry 271, 12814-12819.
47. 3 as its receptor. Journal of Virology 72, 3587-3594.
48. Novella, I. S., Borrego, B., Mateu, M. G., Domingo, E., Giralt, E. & Andreu, D. (1993). Use of substituted and tandem-repeated peptides to probe the relevance of the highly conserved RGD tripeptide in the immune response against foot-and-mouth disease virus. FEES Letters 330, 253-259.
49. Novella, I. S., Duarte, E. A., Elena, S. F., Moya, A., Domingo, E. & Holland, J. J. (1995). Exponential increases of RNA virus fitness during large population transmissions. Proceedings of the National Academy of Sciences, USA 92, 5841-5844.
50. Pereira, H. G. (1977). Subtyping of foot-and-mouth disease virus. In Developments in Biological Standardization, vol. 35, pp. 167-174. Edited by C. Mackowiak & R. H. Regamey. Basel: Karger.
51. Pereira, H. G. (1981). Foot-and-mouth disease. In Virus Diseases of Food Animals, vol. 2, pp. 333-363. Edited by E. P. G. Gibbs. New York: Academic Press.
52. Pfaff, M. (1997). Recognition sites of RGD-dependent integrins. In Integrin-Ligand Interaction, pp. 101-121 Edited by J. A. Eble & K. Kühn. Austin: R. G. Landes.
53. Pfaff, E., Mussgay, M., Böhm, H. O., Schulz, G. E. & Schaller, H. (1982). Antibodies against a preselected peptide recognize and neutralize foot-and-mouth disease virus. EMBO Journal 1, 869-874.
54. 1 Caseros after serial passage in the presence of antiviral polyclonal sera. Journal of Virology 66, 3368-3372.
55. Rowlands, D. J., Clarke, B. E., Carroll, A. R., Brown, F., Nicholson, B. H., Bittle, J. L., Houghten, R. A. & Lerner, R. A. (1983). Chemical basis of antigenic variation in foot-and-mouth disease virus. Nature 306, 694-697.
56. Sa-Carvalho, D., Rieder, E., Baxt, B., Rodarte, R., Tanuri, A. & Mason, P. (1997). Tissue culture adaptation of foot-and-mouth disease virus selects viruses that bind to heparin and are attenuated in cattle. Journal of Virology 71, 5115-5123.
57. Sobrino, F., Dávila, M., Ortín, J. & Domingo, E. (1983). Multiple genetic variants arise in the course of replication of foot-and-mouth disease virus in cell culture. Virology 128, 310-318.
58. Strohmaier, K., Franze, R. & Adam, K.-H. (1982). Location and characterization of the antigenic portion of the FMDV immunizing protein. Journal of General Virology 59, 295-306.
59. Taboga, O., Tami, C., Carrillo, E., Núnez, J. I., Rodríguez, A., Saiz, J. C., Blanco, E., Valero, M.-L., Roig, X., Camarero, J. A., Andreu, D., Mateu, M. G., Giralt, E., Domingo, E., Sobrino, F. & Palma, E. L. (1997). A large scale evaluation of peptide vaccines against foot-and-mouth disease: lack of solid protection in cattle and isolation of escape mutants. Journal of Virology 71, 2606-2614.
60. Verdaguer, N., Mateu, M. G., Andreu, D., Giralt, E., Domingo, E. & Fita, I. (1995). Structure of the major antigenic loop of foot-and-mouth disease virus complexed with a neutralizing antibody: direct involvement of the Arg-Gly-Asp motif in the interaction. EMBO Journal 14, 1690-1696.
61. Verdaguer, N., Mateu, M. G., Bravo, J., Domingo, E. & Fita, I. (1996). Induced pocket to accommodate the cell attachment Arg-Gly-Asp motif in a neutralizing antibody against foot-and-mouth disease virus. Journal of Molecular Biology 256, 364-376.
62. Verdaguer, N., Sevilla, N., Valero, M. L., Stuart, D., Brocchi, E., Andreu, D., Giralt, E., Domingo, E., Mateu, M. G. & Fita, I. (1998). A similar pattern of interaction for different antibodies with a major antigenic site of foot-and-mouth disease virus: Implications for intratypic antigenic variation. Journal of Virology 72, 739-748.
63. Verdaguer, N., Schoehn, G., Ochoa, W. F., Fita, I., Brookes, S., King, A. M. Q., Domingo, E., Mateu, M. G., Stuart, D. & Hewat, E. A. (1999). Flexibility of the major antigenic loop of foot-and-mouth disease virus bound to an Fab fragment of neutralizing antibody: structure and neutralization. Virology 355, 260-268.
64. Vosloo, W., Bastos, A. D., Kirkbride, E., Esterhuysen, J. J., Janse van Rensburg, D., Bengis, R. G., Keet, D. W. & Thomson, G. R. (1996). Persistent infection of African buffalo (Syncerus caffer) with SAT-type foot-and-mouth disease viruses: rate of fixation of mutations, antigenic change and interspecies transmission. Journal of General Virology 77, 1457-1467.