Scanning Mutagenesis Reveals Roles for Helix N of the Bacteriophage T7 RNA Polymerase Thumb Subdomain in Transcription Complex Stability, Pausing, and Termination

Journal of Biological Chemistry

Volumn 276, Issue 13, 2001, Pages 10306-10313

  Brieba, Luis G ^b   Gopal, Vijaya ^b   Sousa, Rui ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MUTAGENESIS; RNA;

SIDE CHAINS;

ENZYMES;

ALANINE; AMINO ACID; ARGININE; ASPARTIC ACID; DNA; RNA; RNA POLYMERASE; SERINE; TRANSCRIPTION FACTOR; TYROSINE; BACTERIOPHAGE T7 RNA POLYMERASE; DNA DIRECTED RNA POLYMERASE; MESSENGER RNA; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIOPHAGE T7; COMPLEX FORMATION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA STRUCTURE; AMINO ACID SEQUENCE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; ESCHERICHIA COLI; GENE DELETION; GENETIC TRANSCRIPTION; METABOLISM; MOLECULAR GENETICS; MUTATION; PROMOTER REGION; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; TIME;

AMINO ACID SEQUENCE; ARGININE; CATALYSIS; DNA-DIRECTED RNA POLYMERASES; ESCHERICHIA COLI; GENE DELETION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEIC ACID CONFORMATION; PROMOTER REGIONS (GENETICS); PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RNA; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; TIME FACTORS; TRANSCRIPTION, GENETIC; VIRAL PROTEINS;

EID: 0035971214     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009866200     Document Type: Article

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