Estrogen receptor-KRAB chimeras are potent ligand-dependent repressors of estrogen-regulated gene expression

Journal of Biological Chemistry

Volumn 275, Issue 18, 2000, Pages 13493-13501

  De Haan, Georgius ^a,c   Chusacultanachai, Sudsanguan ^a,d   Mao, Chengjian ^a   Katzenellenbogen, Benita S ^b   Shapiro, David J ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c WYETH AYERST RESEARCH   (United States)

^d NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; LIGAND; TRICHOSTATIN A;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHIMERA; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENE INSERTION; GENE MUTATION; GENE REPRESSION; GENETIC SELECTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN;

DNA-BINDING PROTEINS; ESTROGENS; GENE EXPRESSION REGULATION; GENE TARGETING; HUMANS; LIGANDS; RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; ZINC FINGERS;

ANIMALIA; ASTEROIDEA;

EID: 0034607833     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.18.13493     Document Type: Article

References (58)

1. Jordan, V. C., and Morrow, M. (1999) Endocr. Rev. 20, 253-278
2. Ince, B. A., Zhuang, Y., Wrenn, C. K., Shapiro, D. J., and Katzenellenbogen, B. S. (1993) J. Biol. Chem. 268, 14026-14032
3. Tzukerman, M. T., Esty, A., Santiso-Mere, D., Danielian, P., Parker, M. G., Stein, R. B., Pike, J. W., and McDonnell, D. P. (1994) Mol. Endocrinol. 8, 21-30
4. Webb, P., Nguyen, P., Shinsako, J., Anderson, C., Feng, W., Nguyen, M. P., Chen, D., Huang, S. M., Subramanian, S., McKinerney, E., Katzenellenbogen, B. S., Stallcup, M. R., and Kushner, P. J. (1998) Mol. Endocrinol. 12, 1605-1618
5. Schodin, D. J., Zhuang, Y., Shapiro, D. J., and Katzenellenbogen, B. S. (1995) J. Biol. Chem. 270, 31163-31171
6. Bellefroid, E. J., Poncelet, D. A., Lecocq, P. J., Revelant, O., and Martial, J. A. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 3608-3612
7. Margolin, J. F., Friedman, J. R., Meyer, W. K.-H., Vissing, H., Thiesen, H.-J., and Rauscher, F. J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 4509-4513
8. Thiesen, H.-J. (1990) New Biol. 2, 363-374
9. Vissing, H., Meyer, W. K.-H., Aagaard, L., Tommerup, N., and Thiesen, H.-J. (1995) FEBS Lett. 369, 153-157
10. Pengue, G., and Lania, L. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 1015-1020
11. Moosmann, P., Georgiev, O., Thiesen, H.-J., Hagmann, M., and Schaffner, W. (1997) Biol. Chem. 378, 669-677
12. Witzgall, R., O'Leary, E., Leaf, A., Onaldi, D., and Bonventre, J. V. (1994) Proc. Natl. Acad. Sci. U. S.A. 91, 4514-4518
13. Moosmann, P., Georgiev, O., Le Douarin, B., Bourquin, J. P., and Schaffner, W. (1996) Nucleic Acids Res. 24, 4859-4867
14. Deuschle, U., Meyer, W. K.-H., and Thiesen, H.-J. (1995) Mol. Cell. Biol. 15, 1907-1914
15. Berry, M., Nunez, A. M., and Chambon, P. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 1218-1222
16. Chusacultanachai, S., Glenn, K. A., Rodriguez, A. O., Reed, E. K., Gardner, J. F., Katzenellenbogen, B. S., and Shapiro, D. J. (1999) J. Biol. Chem. 274, 23591-23598
17. Mader, S., Kumar, V., de Verneuil, H., and Chambon, P. (1989) Nature 338, 271-274
18. Mattick, S., Glenn, K., de Haan, G., and Shapiro, D. J. (1997) J. Steroid Biochem. Mol. Biol. 60, 285-294
19. Lillie, J. W., and Green, M. R. (1989) Nature 338, 39-44
20. Barkhem, T., Andersson-Ross, C., Höglund, M., and Nilsson, S. (1997) J. Steroid Biochem. Mol. Biol. 62, 53-64
21. Friedman, J. R., Fredericks, W. J., Jensen, D. E., Speicher, D. W., Huang, X.-P., Neilson, E. G., and Rauscher, F. J. R. (1996) Genes Dev. 10, 2067-2078
22. Kim, S.-S., Chen, Y.-M., O'Leary, E., Witzgall, R., Vidal, M., and Bonventre, J. V. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 15299-15304
23. Le Douarin, B., Zechel, C., Garnier, J. M., Lutz, Y., Tora, L., Pierrat, P., Heery, D., Gronemeyer, H., Chambon, P., and Losson, R. (1995) EMBO J. 14, 2020-2033
24. McInerney, E. M., and Katzenellenbogen, B. S. (1996) J. Biol. Chem. 271, 24172-24178
25. Metzger, D., Ali, S., Bornert, J. M., and Chambon, P. (1995) J. Biol. Chem. 270, 9535-9542
26. Le Douarin, B., You, J., Nielsen, A. L., Chambon, P., and Losson, R. (1998) J. Steroid Biochem. Mol. Biol. 65, 43-50
27. Yoshida, M., Kijima, M., Akita, M., and Beppu, T. (1990) J. Biol. Chem. 265, 17174-17179
28. Schlake, T., Klehr-Wirth, D., Yoshida, M., and Beppu, T. (1994) Biochemistry 33, 4197-4206
29. Mosselman, S., Polman, J., and Dijkema, R. (1996) FEBS Lett. 392, 49-53
30. Kuiper, G. G., Enmark, E., Pelto-Huikko, M., Nilsson, S., and Gustafsson, J. A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 5925-5930
31. McInerney, E. M., Weis, K. E., Sun, J., Mosselman, S., and Katzenellenbogen, B. S. (1998) Endocrinology 139, 4513-4522
32. Brock, M. L., and Shapiro, D. J. (1983) J. Biol. Chem. 258, 5449-5455
33. Shiau, A. K., Barstad, D., Loria, P. M., Cheng, L., Kushner, P. J., Agard, D. A., and Greene, G. L. (1998) Cell 95, 927-937
34. Dauvois, S., White, R., and Parker, M. G. (1993) J. Cell Sci. 106, 1377-1388
35. Devin-Leclerc, J., Meng, X., Delahaye, F., Leclerc, P., Baulieu, E.-E., and Catelli, M.-G. (1998) Mol. Endocrinol. 12, 842-854
36. Metzger, D., Berry, M., Ali, S., and Chambon, P. (1995) Mol. Endocrinol. 9, 579-591
37. Wang, Y., Xu, J., Pierson, T., O'Malley, B. W., and Tsai, S. Y. (1997) Gene Ther. 4, 432-441
38. Pengue, G., Calabro, V., Bartoli, P. C., Pagliuca, A., and Lania, L. (1994) Nucleic Acids Res. 22, 2908-2914
39. Maloy, S., and Youderian, P. (1994) Methods Mol. Genet. 3, 205-233
40. Rio, M. C., and Chambon, P. (1990) Cancer Cells 2, 269-274
41. Nardulli, A. M., Romine, L. E., Carpo, C., Greene, G. L., and Rainish, B. (1996) Mol. Endocrinol. 10, 694-704
42. Pengue, G., Caputo, A., Rossi, C., Barbanti-Brodano, G., and Lania, L. (1995) J. Virol. 69, 6577-6580
43. Clarke, R., and Brunner, N. (1996) Trends Endocrinol. Metab. 7, 291-301
44. Lippman, M. E., Dickson, R. B., Gelmann, E. P., Rosen, N., Knabbe, C., Bates, S., Bronzert, D., Huff, K., and Kasid, A. (1987) J. Cell. Biochem. 35, 1-16
45. Dickson, R. B., and Lipmann, M. E. (1997) in Cancer: Principles & Practice of Oncology (De Vita, V. T. J., Hellman, S., and Rosenberg, S. A., eds) 5th Ed., Vol. 1, pp. 1541-1556, Lippincot-Raven Publishers, Philadelphia
46. Zhuang, Y., Katzenellenbogen, B. S., and Shapiro, D. J. (1995) Mol. Endocrinol. 9, 457-466
47. Xing, H., and Shapiro, D. J. (1993) J. Biol. Chem. 268, 23227-23233
48. Reese, J. C., and Katzenellenbogen, B. S. (1992) Mol. Cell. Biol. 12, 4531-4538
49. Katzenellenbogen, J. A., O'Malley, B. W., and Kalzenellenbogen, B. S. (1997) Mol. Endocrinol. 10, 119-131
50. Dauvois, S., Danielian, P. S., White, R., and Parker, M. G. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 4037-4041
51. Cheskis, B. J., Karathanasis, S., and Lyttle, C. R. (1997) J. Biol. Chem. 272, 11384-11391
52. Ichinose, H., Garnier, J. M., Chambon, P., and Losson, R. (1997) Gene (Amst.) 188, 95-100
53. Cavalli, G., and Paro, R. (1998) Curr. Opin. Cell Biol. 10, 354-360
54. Ma, Z. Q., Tsai, M. J., and Tsai, S. Y. (1999) J. Steroid Biochem. Mol. Biol. 69, 155-163
55. Chien, P. Y., Ito, M., Park, Y., Tagami, T., Gehm, B. D., and Jameson, J. L. (1999) Mol. Endocrinol. 13, 2122-2136
56. Ponglikitmongkol, M., White, J. H., and Chambon, P. (1990) EMBO J. 9, 2221-2231
57. Greisman, H. A., and Pabo, C. O. (1997) Science 275, 657-661
58. Segal, D. J., Dreier, B., Beerli, R. R., and Barbas, C. F. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 2758-2763