Hibernation-induction peptide and cell death: [D-Ala2,D-Leu5]enkephalin blocks Bax-related apoptotic processes

European Journal of Pharmacology

Volumn 428, Issue 1, 2001, Pages 149-151

  Tsao, Li I ^a   Su, Tsung Ping ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

D Ala2,D Leu5 enkephalin (DADLE); Bax; Methamphetamine

Indexed keywords

CYTOCHROME C; ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE]; METHAMPHETAMINE; PROTEIN BAX;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL DEATH; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; CYTOSOL; DRUG EFFECT; HIBERNATION; MALE; MITOCHONDRION; MOUSE; NEUROPROTECTION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN SECRETION;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CENTRAL NERVOUS SYSTEM STIMULANTS; CYTOCHROME C GROUP; CYTOSOL; ENKEPHALIN, LEUCINE-2-ALANINE; MALE; METHAMPHETAMINE; MICE; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, OPIOID, DELTA;

EID: 0035964729     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)01346-2     Document Type: Article

References (8)

1. Peptide transport systems for opiates across the blood-brain barrier
2. Bcl-2 family proteins
3. Methamphetamine and methylenedioxymethamphetamine neurotoxicity: Possible mechanisms of cell destruction
4. Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspase-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
5. Amphetamine induces apoptosis and regulation of bcl-x splice variants in neocortical neurons
6. Delta opioid peptide [D-Ala2,D-Leu5]enkephalin promotes cell survival
7. Delta opioid peptide [D-Ala2,D-Leu5]enkephalin blocks the long-term loss of dopamine transporters induced by multiple administration of methamphetamine: Involvement of opioid receptors and reactive oxygen species
8. Prevention of apoptosis by bcl-2: Release of cytochrome c from mitochondria blocked