Phenotypic alterations in Caki-1 Cells as a consequence of TIMP-1 overexpression

Cancer Letters

Volumn 169, Issue 2, 2001, Pages 189-198

  Reid, H M ^a   McElligott, A M ^b   McGlynn, H ^a  

^a UNIVERSITY OF ULSTER   (United Kingdom)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Cell adhesion; Cell cycle; Invasion; Tissue inhibitor of metalloproteinase 1

Indexed keywords

COLLAGEN TYPE 4; FIBRONECTIN; INTEGRIN; LAMININ; LIPOFECTAMINE; MATRIGEL; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ARTICLE; CELL ADHESION; CELL CYCLE; CELL INVASION; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CLONE; CONTROLLED STUDY; DOSE RESPONSE; EXTRACELLULAR MATRIX; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BLOTTING, WESTERN; CELL ADHESION; CELL CYCLE; CELL DIVISION; CELL MOVEMENT; CELL SURVIVAL; COLLAGEN; DRUG COMBINATIONS; EXTRACELLULAR MATRIX; FIBRONECTINS; FLOW CYTOMETRY; HUMANS; LAMININ; PHENOTYPE; PROTEASE INHIBITORS; PROTEOGLYCANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035964488     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(01)00520-1     Document Type: Article

References (40)

1. Regulation of development and differentiation by the extracellular matrix
2. The extracellular matrix as a cell survival factor
3. Insights into MMP-TIMP interactions
4. Proteolytic remodeling of extracellular matrix
5. Physiological roles of matrix metalloproteinases: Implications for tumor growth and metastasis
6. Matrix metalloproteinases. Novel targets for directed cancer therapy
7. Identification and characterization of a novel human matrix metalloproteinase with unique structural characteristics, chromosomal location, and tissue distribution
8. Isolation and characterization of two novel metalloproteinase genes linked to the Cdc2L locus on human chromosome 1p36.3
9. Cloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family members
10. Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP
11. Membrane-type 6 matrix metalloproteinase (MT6-MMP, MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored MMP
12. Identification and characterization of human endometase (Matrix metalloproteinase-26) from endothetrial tumor
13. Cell-cell and cell-stromal interactions in breast cancer invasion and metastasis review
14. Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions
15. Expression and activity of MMPs and their regulators in ovarian cancer
16. Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells
17. A switch from stromal to tumor cell expression of stromolysin-1 mRNA associated with the conversion of squamous to spindle carcinomas during mouse skin tumor progression
18. Up-regulated expression of the β3 integrin and the 92-kDa gelatinase in human HT-144 melanoma cell tumors
19. Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells
20. Integrins: Versatility, modulation and signalling in cell adhesion
21. Anti-α3 integrin antibody induces the activated form of matrix metalloproteinase-2 (MMP-2) with concomitant stimulation of invasion through Matrigel by human Rhabdomyosarcoma cells
22. Role of ανβ3 integrin in human melanoma invasion
23. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression
24. Integrin α2β1 is a positive regulator of collagenase (MMP-1) and collagen α1 (I) gene expression
25. Localisation of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin ανβ3
26. Matrix metalloproteinase-2 activation modulates glioma cell migration
27. Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases
28. Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2
29. Tissue inhibitor of metalloproteinase-2 stimulates fibroblast via a cAMP-dependant mechanism
30. Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro
31. Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3
32. TIMP-3 induces cell death by stabilizing TNF-α receptors on the surface of human colon carcinoma cells
33. Composition of extracellular matrix and distribution of cell adhesion molecules in renal cell tumors
34. In vivo distribution of integrins in renal cell carcinoma: Integrin-phenotype alteration in different degrees of tumor differentiation and VLA-2 involvement in tumor metastasis
35. Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas
36. Directed mutagenesis reveals that two histidines in tissue inhibitor of metalloproteinase-1 are each essential for the suppression of cell migration, invasion, and tumorigenicity
37. Tissue inhibitor of metalloproteinase (TIMP)-1 induces differentiation and an antiapoptotic phenotype in germinal center B cells
38. In vitro suppression of programmed cell death of B cells by tissue inhibitor of metalloproteinase-1
39. CAS/CRK coupling serves as a 'molecular switch' for induction of cell migration
40. Regulation of integrin function