L-tyrosine and nitric oxide synergize to prevent cytotoxic effects of superoxide

Toxicology

Volumn 165, Issue 2-3, 2001, Pages 163-170

  Souici, Anne Christine ^a   Fitzhugh, Anthony L ^b   Keefer, Larry K ^c   Felley Bosco, Emanuela ^a  

^a University of Lausanne Departement de Pharmacologie et de Toxicologie   (Switzerland)

^b SAIC FREDERICK INC   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Epithelial cells; L Tyrosine; Nitric oxide; Oxidative damage; Reactive nitrogen species; Reactive oxygen species

Indexed keywords

DNA FRAGMENT; HYPOXANTHINE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITROGEN DERIVATIVE; REACTIVE NITROGEN SPECIES; SODIUM 1 (N,N DIETHYLAMINO)DIAZEN 1 IUM 1,2 DIOLATE; SUPEROXIDE; TYROSINE; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

ANTIOXIDANT ACTIVITY; ARTICLE; BRONCHUS MUCOSA; CANCER CELL CULTURE; CELL PROTECTION; CELL STRAIN CACO 2; CELL SURVIVAL; COLON ADENOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; LIPID PEROXIDATION; NITRATION; PRIORITY JOURNAL;

BRONCHI; CACO-2 CELLS; CELL LINE; CELL SURVIVAL; DNA DAMAGE; DRUG SYNERGISM; HUMANS; HYDRAZINES; HYPOXANTHINE; LIPID PEROXIDATION; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROGEN OXIDES; REACTIVE OXYGEN SPECIES; SUPEROXIDES; TYROSINE; XANTHINE OXIDASE;

EID: 0035964437     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(01)00428-0     Document Type: Article

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