Pathogenesis, diagnosis and treatment of systemic amyloidosis

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 356, Issue 1406, 2001, Pages 203-211

  Pepys, M B ^a   Kelly, J W ^a   Lindquist, S ^a   Dobson, C M ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Amyloidosis; Diagnosis; Serum amyloid P component; Treatment

Indexed keywords

EID: 0035961291     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.2000.0766     Document Type: Conference Paper

References (67)

1. Extensive intimal apolipoprotein A1-derived amyloid deposits in a patient with an apolipoprotein A1 mutation
2. Differences in the acute phase responses of serum amyloid P component (SAP) and C3 to injections of casein or bovine serum albumin in amyloid-susceptible and resistant mouse strains
3. A new apolipoprotein AI variant, Trp50Arg, causes hereditary amyloidosis
4. Hereditary hepatic and systemic amyloidosis caused by a new deletion/insertion mutation in the apolipoprotein AI gene
5. Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis
6. Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene
7. Mechanistic studies of the folding of human lysozyme and the origin of amyloidogenic behavior in its disease-related variants
8. Designing conditions for in vitro formation of amyloid protofilaments and fibrils
9. Hamster female protein, a sex-limited pentraxin, is a constituent of Syrian hamster amyloid
10. Amyloidosis and female protein in the Syrian hamster. Concurrent regulation by sex hormones
11. Electron microscopic observations on a fibrous component in amyloid of diverse origins
12. Structure of pentameric human serum amyloid P component
13. Amyloidosis: A review of recent diagnostic and therapeutic developments
14. Allogeneic bone marrow transplantation for systemic AL amyloidosis
15. Hereditary renal amyloidosis associated with variant lysozyme in a large English family
16. Curative hepatorenal transplantation for systemic amyloidosis associated with fibrinogen α-chain Glu526Val in an English family
17. Cumulative SAA production and outcome of AA amyloidosis
18. β-pleated sheet fibrils. A comparison of native amyloid with synthetic protein fibrils
19. Cardiac transplantation for AL amyloidosis: A personal account
20. Hereditary amyloid cardiomyopathy caused by a variant apolipoprotein Al
21. A novel apolipoprotein A-1 variant, Arg173Pro, associated with cardiac and cutaneous amyloidosis
22. The diagnosis, natural history and treatment of amyloidosis. The Goulstonian Lecture 1995
23. Diagnostic radionuclide imaging of amyloid: Biological targeting by circulating human serum amyloid P component
24. 123I-labeled serum amyloid P component
25. Metabolic studies of radioiodinated serum amyloid P component in normal subjects and patients with systemic amyloidosis
26. Scintigraphic quantification and serial monitoring of human visceral amyloid deposits provide evidence for turnover and regression
27. Serum amyloid P component scintigraphy and turnover studies for diagnosis and quantitative monitoring of AA amyloidosis in juvenile rheumatoid arthritis
28. Specific chemical dissociation of fibrillar and non-fibrillar components of amyloid deposits
29. Binding specificity of serum amyloid P component for the pyruvate acetal of galactose
30. Crystal structure of a decameric complex of human serum amyloid P component with bound dAMP
31. 30)
32. Clinical improvement and amyloid regression after liver transplantation in hereditary transthyretin amyloidosis
33. Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing
34. New USA family has apolipoprotein AI (Arg26) variant
35. Alternative conformations of amyloidogenic proteins govern their behaviour
36. 2--binding region of human serum amyloid P component and other pentraxins
37. Arresting amyloidosis in vivo using small molecule anionic sulphonates or sulphates: Implications for Alzheimer's disease
38. Formation of amyloid-like fibrils by self-association of a partially unfolded fibronectin type III module
39. β-amyloid neurotoxicity requires fibril formation and is inhibited by Congo red
40. Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus
41. Interaction of the anthracycline 4′-iodo-4′-deoxydoxorubicin with amyloid fibrils: Iinhibition of amyloidogenesis
42. 2-microglobulin from urine
43. A mutation in apolipoprotein A-I in the Iowa type of familial amyloidotic polyneuropathy
44. 174→Ser causes hereditary cardiac amyloidosis, and the amyloid fibrils are constituted by the 93-residue N-terminal polypeptide
45. Amyloidosis
46. Amyloidosis
47. The Lumleian Lecture. C-reactive protein and amyloidosis: From proteins to drugs?
48. Human serum amyloid P component is an invariant constituent of amyloid deposits and has a uniquely homogeneous glycostructure
49. Amyloid P component. A critical review
50. Hereditary nephropathic systemic amyloidosis caused by a novel variant apolipoprotein A-I
51. Inhibiting transthyretin conformational changes that lead to amyloid fibril formation
52. The first international standard for serum amyloid A protein (SAA). Evaluation in an international collaborative study
53. Serum amyloid P component scintigraphy in familial amyloid polyneuropathy: Regression of visceral amyloid following liver transplantation
54. Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vivo
55. Experimental amyloidosis in the hamster: Correlation between hamster female protein levels and amyloid deposition
56. Plaque busters: Strategies to inhibit amyloid formation in Alzheimer's disease
57. Apolipoprotein AI mutation Arg-60 causes autosomal dominant amyloidosis
58. A superfamily of proteins with the lectin fold
59. Domino hepatic transplantation using the liver from a patient with familial amyloid polyneuropathy
60. Progressive cardiac amyloidosis following liver transplantation for familial amyloid polyneuropathy
61. Common core structure of amyloid fibrils by synchrotron X-ray diffraction
62. Long term effect of renal transplantation on dialysis-related amyloid deposits and symptomatology
63. Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer's disease and systemic amyloidosis
64. The physiological structure of human C-reactive protein and its complex with phosphocholine
65. Familial nephropathic systemic amyloidosis caused by apolipoprotein AI variant Arg26
66. Rapid regression of AA amyloidosis following surgery for Castleman's disease
67. Apolipoprotein AI-derived amyloid in human aortic atherosclerotic plaques