Iron-induced changes in nitric oxide and superoxide radical generation in rat liver after lindane or thyroid hormone treatment

Toxicology Letters

Volumn 119, Issue 2, 2001, Pages 87-93

  Cornejo, Pamela ^a   Tapia, Gladys ^a   Puntarulo, Susana ^b   Galleano, Mónica ^b   Videla, Luis A ^a   Fernández, Virginia ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Iron overload; Lindane; Nitric oxide; Rat liver; Superoxide radical; Thyroid hormone

Indexed keywords

CARBONYL DERIVATIVE; DEFEROXAMINE; IRON; LINDANE; LIOTRIX; LIVER PROTEIN; NITRIC OXIDE; SUPEROXIDE; THYROID HORMONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HYPERTHYROIDISM; IRON OVERLOAD; LIVER TOXICITY; MALE; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; RAT;

ANIMALS; IRON; LINDANE; LIVER; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDES; THYROID HORMONES;

ANIMALIA;

EID: 0035961229     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(00)00295-2     Document Type: Article

References (31)

1. Role of metals in oxygen radical reactions
2. Differential effects of short-term lindane administration on parameters related to oxidative stress in rat liver and erythrocytes
3. Derangement of Kupffer cell functioning and hepatotoxicity in hyperthyroid rats subjected to acute iron overload
4. Lipid peroxidation and associated hepatic organelle dysfunction in iron overload
5. Evidence suggesting that nitric oxide mediates iron-induced toxicity in cultured proximal tubule cells
6. Regulation of hepatic nitric oxide synthase by reactive oxygen intermediates and glutathione
7. Influence of hyperthyroidism on superoxide radical and hydrogen peroxide production by rat liver submitochondrial particles
8. Superoxide radical formation, NADPH oxidase activity, and cytochrome p450 content of rat liver microsomal fractions in an experimental hyperthyroid state: Relation to lipid peroxidation
9. Influence of hyperthyroidism on the activity of liver nitric oxide synthase in the rat
10. Hepatic chemiluminescence and lipid peroxidation in mild iron overload
11. Induction of lipid peroxidation by hexachlorocyclohexane, dieldrin, TCDD, carbon tetrachloride and chlorobenzene in rats
12. Role of the hepatic xanthine oxidase in thyroid dysfunction: Effect of thyroid hormones in oxidative stress in rat liver
13. Lindane-induced liver oxidative stress. I. Antioxidant enzymes, lipid peroxidation indexes, and morphologic characteristics
14. Regression of morphological alterations and oxidative stress-related parameters after acute lindane-induced hepatotoxicity in rats
15. Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat
16. Nitric oxide synthases in mammals
17. Lipid peroxidation in rat liver microsomes. I. Stimulation of NADPH-cytochrome P450 reductase-dependent process in hyperthyroid state
18. Role of iron in NF-κB activation and cytokine gene expression by rat hepatic macrophages
19. Protein measurement with Folin phenol reagent
20. Activation of lipid peroxidation in liver mitochondria of hyperthyroid rabbits
21. Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liver-derived tissues
22. Oxidative damage to proteins: Spectrophotometric method for carbonyl assay
23. Time course study of the influence of acute iron overload on Kupffer cell functioning and hepatotoxicity assessed in the isolated perfused rat liver
24. Protein oxidation in thyroid hormone-induced liver oxidative stress: Relation to lipid peroxidation
25. Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria
26. Effect of thyroid state on lipid peroxidation, antioxidant defenses, and susceptibility to oxidative stress in rat tissues
27. Lindane-induced liver oxidative stress
28. Influence of hyperthyroidism on lindane-induced hepatotoxicity in the rat
29. Energy metabolism, thyroid calorigenesis and oxidative stress: Functional and cytotoxic consequences
30. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase activity by interferon γ and bacterial lipopolysaccharide
31. Lindane-induced rat liver lipid peroxidation without depressed Cu-Zn superoxide dismutase activities