Time course study of the influence of acute iron overload on kupffer cell functioning and hepatotoxicity assessed in the isolated perfused rat liver

Hepatology

Volumn 27, Issue 5, 1998, Pages 1311-1316

  Tapia, Gladys ^a   Troncoso, Filar ^a   Galleano, Monica ^b   Fernandez, Virginia ^a   Puntarulo, Susana ^b   Videla, Luis A ^a,c  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c UNIVERSITY OF CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

IRON;

ANIMAL TISSUE; ARTICLE; CELL RESPIRATION; CONTROLLED STUDY; IRON OVERLOAD; ISOLATED LIVER; KUPFFER CELL; LIVER TOXICITY; MACROPHAGE ACTIVATION; MALE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; RESPIRATORY BURST;

ACUTE DISEASE; ANIMALS; CARBON; GADOLINIUM; IRON; IRON OVERLOAD; KUPFFER CELLS; L-LACTATE DEHYDROGENASE; LIVER DISEASES; MALE; OXYGEN CONSUMPTION; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 0031971086     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510270517     Document Type: Article

References (34)

1. Britton RS, Bacon BR, Recknagel RO. Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem Phys Lipids 1987;45:207-239.
2. Aust SD, Morehouse LA, Thomas CE. Role of metals in oxygen radical reactions. J Free Radic Biol Med 1985;1:3-25.
3. Bacon BR, Tavill AS. Role of the liver in normal iron metabolism. Semin Liver Dis 1984;4:181-192.
4. 2. In: Poli G, Cheeseman KH, Dianzani MU, Slater TF, eds. Free Radicals in Liver Injury. Oxford, IRL, 1985:127-134.
5. Lee YH, Layman DK, Bell RR, Norton HW. Responses of glutathione peroxidase and catalase to excess dietary iron in rats. J Nutr 1981;111:2195-2202.
6. Masini A, Trenti T, Ventura E, Ceccarelli-Stanzani D, Muscatello V. Functional efficiency of mitochondrial membrane of rats with hepatic chronic iron overload. Biochem Biophys Res Commun 1984;124:462-469.
7. Wills DE. Effects of iron overload on lipid peroxide formation and oxidative demethylation by the liver endoplasmic reticulum. Biochem Pharmacol 1972;21:239-247.
8. Videla LA, Fernández V, Valenzuela A. Effect of ethanol and iron on the hepatic and biliary levels of glutathione and lipid peroxidative indexes. Alcohol 1985;2:457-462.
9. Goddard JG, Basford D, Sweeney GD. Lipid peroxidation stimulated by iron nitrilotriacetate in rat liver. Biochem Pharmacol 1986;35:2381-2387.
10. Filser JG, Bolt HM, Mulliawan H, Kappus H. Quantitative evaluation of ethane and n-pentane as indicators of lipid peroxidation in vivo. Arch Toxicol 1983;52:135-147.
11. Galleano M, Puntarulo S. Hepatic chemiluminescence and lipid peroxidation in mild iron overload. Toxicology 1992;76:27-38.
12. Murphy ME, Sies H. Visible-range low-level chemiluminescence in biological systems. Methods Enzymol 1990;186:595-610.
13. Searle JW, Kerr JFR, Halliday JW, Powell LW. Iron storage disease. In: MacSween RNM, Anthony PP, Scheuer PJ, eds. Pathology of the liver. New York: Churchill Livingstone, 1987:181-201.
14. Ley TJ, Griffith F, Nienhuis AW. Transfusion haemosiderosis and chelation therapy. Clin Haematol 1982;11:437-464.
15. Decker K. Biologically active products of stimulated liver macrophages (Kupffer cells). Eur J Biochem 1990;192:245-262.
16. Hardonk MJ, Dijkhuis FWJ, Hulstaert CE, Koudstaal J. Heterogeneity of rat liver and spleen macrophages in gadolinium chloride-induced elimination and repopulation. J Leukoc Biol 1992;52:296-302.
17. Persijn JP, Van der Slik W, Riethorst A. Determination of serum iron and latent iron-binding capacity (LIBC). Clin Chim Acta 1971;35:91-98.
18. Brumby PE, Massey V. Determination of nonheme iron, total iron and copper. Methods Enzymol 1967;10:463-472.
19. Rothman-Sherman A, Tschiember-Tissue N. Tissue iron, copper and zinc levels in offspring of iron-sufficient and iron-deficient rats. J Nutr 1981;111:266-275.
20. Tapia G, Pepper I, Smok G, Videla LA. Kupffer cell function in thyroid hormone-induced liver oxidative stress in the rat. Free Radic Res 1997;26:267-279.
21. Bergmeyer HU, Bernt E. Lactate dehydrogenase. In: Bergmeyer HU, ed. Methods of Enzymatic Analysis. Vol. 2. New York: Academic, 1974:574-579.
22. Cowper KB, Currin RT, Dawson TL, Lindert KA, Lemasters JJ, Thurman RG. A new method to monitor Kupffer-cell function continuously in the perfused rat liver. Biochem J 1990;266:141-147.
23. Tapia G, Cornejo P, Ferreira J, Fernández V, Videla LA. Acetaminophen-induced liver oxidative stress and hepatotoxicity: influence of Kupffer cell activity assessed in the isolated perfused rat liver. Redox Report 1997;(in press).
24. 2, and HOC1. Arch Biochem Biophys 1993;304:189-196.
25. Ischiropoulos H, Zhu L, Beckman JS. Peroxynitrite formation from activated rat alveolar macrophages. Arch Biochem Biophys 1992;298:446-451.
26. 2 consumption: alcohol and cell-cell communication. Am J Physiol 1996;270:G574-G580.
27. Laskin DL, Gardner CR, Price VF, Jollow DJ. Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen. HEPATOLOGY 1995;21:1045-1050.
28. Blazka ME, Wilmer JL, Holladay SD, Wilson RE, Luster MI. Role of proinflammatory cytokines in acetaminophen hepatotoxicity. Toxicol Appl Pharmacol 1995;133:43-52.
29. Jandl RC, André-Schwartz J, Borges-DuBois L, Kipnes RS, McMurrich BJ, Babior BM. Termination of the respiratory burst in human neutrophils. J Clin Invest 1978;61:1176-1185.
30. 2 by iron. Br J Infect Immun 1975;12:303-308.
31. Ambruso DR, Johnston RB Jr. Lactoferrin enhances hydroxyl radical production by human neutrophils particulate fractions, and an enzymatic generating system. J Clin Invest 1981;67:352-360.
32. Weinberg DE. Iron and infection. Microbiol Rev 1978;42:452-462.
33. Van Asbeck BS, Marx JJM, Struyvenberg A, Verhoef J. Functional defects in phagocytic cells from patients with iron overload. J Infect 1984;8:232-240.
34. Bonkovsky HL, Banner BF, Rothman AL. Iron and chronic viral hepatitis. HEPATOLOGY 1997;25:759-768.