Regulation of immunoglobulin E-mediated secretion by protein phosphatases in human basophils and mast cells of skin and lung

European Journal of Pharmacology

Volumn 430, Issue 1, 2001, Pages 135-141

  Bastan, Reza ^a   Peirce, Matthew J ^a   Peachell, Peter T ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Basophil; Fostriecin; Mast cell; Okadaic acid; Protein phosphatase; Tautomycin

Indexed keywords

CALYCULIN A; CYANOGINOSIN; FOSTRIECIN; HISTAMINE RELEASE INHIBITOR; IMMUNOGLOBULIN E; OKADAIC ACID; OKADAOL; OKADAONE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; SERINE; TAUTOMYCIN; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; BASOPHIL; CELL ACTIVITY; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; ENZYME REGULATION; FEMALE; HISTAMINE RELEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; LUNG; MALE; MAST CELL; PRIORITY JOURNAL; SKIN; STRUCTURE ACTIVITY RELATION;

ALKENES; ANTIBIOTICS, ANTIFUNGAL; BASOPHILS; ENZYME INHIBITORS; HISTAMINE RELEASE; HUMANS; IMMUNOGLOBULIN E; LUNG; MAST CELLS; OKADAIC ACID; OXAZOLES; PHOSPHOPROTEIN PHOSPHATASE; PYRANS; PYRONES; SKIN; SPIRO COMPOUNDS;

EID: 0035955397     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)01366-8     Document Type: Article

References (41)

1. Isolation and properties of cardiac and other mast cells from the rat and guinea-pig
2. Signal transduction by Fc receptors: The FcεRI case
3. Protein-tyrosine phosphorylation: An essential component of Fc epsilon RI signalling
4. Effect of okadaic acid on human basophil secretion
5. PPX, a novel protein serine/threonine phosphatase localised to centrosomes
6. A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localises to the nucleus
7. Protein phosphatase 2A activates the proapoptotic function of BAD in interleukin-3-dependent lymphoid cells by a mechanism requiring 14-3-3 dissociation
8. Cyclosporine A rapidly inhibits mediator release from human basophils presumably by interacting with cyclophilin
9. The structure and regulation of protein phosphatases
10. Protein phosphatases come of age
11. An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues
12. Okadaic acid: A new probe for the study of cellular regulation
13. Current techniques of histamine determination: Automated fluorometric assays
14. 3H-dihydromicrocystin-LR, a cyclic peptide toxin
15. Differential inhibition and posttranslational modification of protein phosphatase 1 and 2A in MCF7 cells treated with calyculin-A, okadaic acid and tautomycin
16. Basophil counting with a new staining method using alcian blue
17. Protein tyrosine phosphorylation as a mechanism of signalling in mast cells and basophils
18. Use of okadaic acid to inhibit protein phosphatases in intact cells
19. Purification of protein phosphatase 4 catalytic subunit: Inhibition by the antitumor drug fostriecin and other tumor suppressors and promoters
20. Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism
21. Identification, purification, and characterisation of a novel serine/threonine protein phosphatase from bovine brain
22. Calyculin-A and okadaic acid - Inhibitors of protein phosphatase activity
23. Calcineurin is a common target of cyclophilin cyclosporine-A and FKBP-FK506 complexes
24. Human mast cell heterogeneity: Histamine release from mast cells dispersed from skin, lung, adenoids, tonsils, and colon in response to IgE-dependent and nonimmunologic stimuli
25. Inhibitors of protein kinases and phosphatases
26. Structure-activity relationship within a series of okadaic acid derivatives
27. Phosphorylation and dephosphorylation of the high affinity receptor for immunoglobulin E immediately after receptor engagement and disengagement
28. Regulation of human lung mast cell function by phosphatase inhibitors
29. Mast cell heterogeneity
30. Regulation of human basophil function by phosphatase inhibitors
31. Preliminary characterization of the role of protein serine/threonine phosphatases in the regulation of human lung mast cell function
32. Characterisation of serine/threonine phosphatase activities in human lung mast cells and basophils
33. Effects of protein phosphatase inhibitors on the regulation of insulin-sensitive enzymes within rat epididymal fat-pads and cells
34. Inflammatory mediators and mechanisms of release from purified human basophils and mast cells
35. Protein serine/threonine phosphatases - New avenues for cell regulation
36. An automated continuous-flow system for the extraction and fluorometric analysis of histamine
37. Inhibition of specific binding of okadaic acid to protein phosphatase 2A by microcystin-LR, calyculin-A and tautomycin: Method of analysis of interactions of tight-binding ligands with target protein
38. 2 release from human lung mast cells by cyclosporine-A
39. Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A
40. Pulmonary immune cells in health and disease: Mast cells and basophils
41. Distinct roles for PP1 and PP2A in phosphorylation of the retinoblastoma protein