Aspartic protease inhibitors designed from computer-generated templates bind as predicted

Organic Letters

Volumn 3, Issue 15, 2001, Pages 2309-2312

  Ripka, Amy S ^a   Satyshur, Kenneth A ^a   Bohacek, Regine S ^b   Rich, Daniel H ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Ariad Pharmaceutical   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC PROTEINASE; PEPTIDE; PROTEINASE INHIBITOR; RHIZOPUSPEPSIN;

ARTICLE; CHEMISTRY; COMPUTER SIMULATION; DRUG ANTAGONISM; DRUG DESIGN; METABOLISM; MOLECULAR MIMICRY; PREDICTION AND FORECASTING; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ASPARTIC ENDOPEPTIDASES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; MOLECULAR MIMICRY; PEPTIDES; PREDICTIVE VALUE OF TESTS; PROTEASE INHIBITORS; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035954861     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol016090+     Document Type: Article

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