Transformation of peptides into non-peptides. Synthesis of computer-generated enzyme inhibitors

Chimia

Volumn 51, Issue 1-2, 1997, Pages 45-47

  Rich, Daniel H ^a   Bohacek, Regine S ^b   Dales, Natalie A ^a   Glunz, Peter ^a   Ripka, Amy S ^c  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0038902210     PISSN: 00094293     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. D.H. Rich, 'Peptidase Inhibitors', in 'Comprehensive Medicinal Chemistry. The Rational Design, Mechanistic Study and Therapeutic Application of Chemical Compounds', Eds. C Hansch, P.G. Sammes, and J.B. Taylor, Pergamon Press, Cambridge, 1989, pp. 391-441.
2. e série', Elsevier, Amsterdam, 1996, pp. 101-111.
3. R.S. Bohacek, C. McMartin, J. Am. Chem. Soc. 1994, 116, 5560.
4. L. Chen, J.W. Erickson, T.J. Rydel, C.H. Park, D. Neidhart, J. Luly, C. Abad-Zapatero, Acta Crystallogr., Sect. B 1992, 48, 476.
5. A.B. Smith, M. Fukui, H.A. Vaccaro, J.R. Empfield, J. Am. Chem. Soc. 1991, 113, 2071.
6. a) E.M. Gordon, R.W. Barrett, W.J. Dower, S.P.A. Fodor, M.A. Gallop MA, J. Med. Chem. 1994, 37, 1385;
7. b) M.A. Gallop, R.W. Barrett, W.J. Dower, S.P.A. Fodor, E.M. Gordon, ibid. 1994, 37, 1233.