Semen from boars infected with porcine reproductive and respiratory syndrome virus (PRRSV) contains antibodies against structural as well as nonstructural viral proteins

Veterinary Microbiology

Volumn 81, Issue 2, 2001, Pages 109-125

  Oleksiewicz, M B ^a   Botner A ^a   Normann, P ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Anti PRRSV antibodies; Nonstructural protein; Pig viruses; Porcine reproductive and respiratory syndrome virus; Semen; Structural protein

Indexed keywords

ANTIBODY; EPITOPE; GLYCOPROTEIN; IMMUNOGLOBULIN A; RNA DIRECTED RNA POLYMERASE; STRUCTURAL PROTEIN; VIRUS PROTEIN; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTERIVIRUS; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXCRETION; IMMUNE RESPONSE; NASOPHARYNX; NONHUMAN; NUCLEOTIDE SEQUENCE; SPERM; SWINE; SWINE DISEASE; VIRUS INFECTION;

EID: 0035954834     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1135(01)00341-8     Document Type: Article

References (46)

1. S.F. Altschul T.L. Madden A.A. Schaffer J. Zhang Z. Zhang W. Miller D.J. Lipman Gapped BLAST and PSI-BLAST: a new generation of protein database search programs Nucleic Acids Res. 25 1997 3389 3402
2. Benfield, D., Nelson, B.S., Steffen, M., Rowland, R., 2000. In: Proceedings of the American Association Swine Practicioners, March 11–14 2000, pp. 405–408.
3. A. Bøtner B. Strandbygaard K.J. Sørensen P. Have K.G. Madsen E. Smedegaard Madsen S. Alexandersen Appearance of acute PRRS-like symptoms in sow herds after vaccination with a modified live PRRS vaccine Vet. Rec. 141 1997 497 499
4. C.M. Campero P.W. Ladds D. Hoffmann B. Duffield D. Watson G. Fordyce Immunopathology of experimental Brucella abortus strain 19 infection of the genitalia of bulls Vet. Immunol. Immunopathol. 24 1990 235 246
5. J. Christopher-Hennings E.A. Nelson J.K. Nelson R.J. Hines S.L. Swenson H.T. Hill J.J. Zimmerman J.B. Katz M.J. Yaeger C.C. Chase Detection of porcine reproductive and respiratory syndrome virus in boar semen by PCR J. Clin. Microbiol. 33 1995 1730 1734
6. J. Christopher-Hennings E.A. Nelson R.J. Hines J.K. Nelson S.L. Swenson J.J. Zimmerman C.L. Chase M.J. Yaeger D.A. Benfield Persistence of porcine reproductive and respiratory syndrome virus in serum and semen of adult boars J. Vet. Diag. Invest. 7 1995 456 464
7. J. Christopher-Hennings E.A. Nelson J.K. Nelson D.A. Benfield Effects of modified-live virus vaccine against porcine reproductive and respiratory syndrome in boars Am. J. Vet. Res. 58 1997 40 45
8. J. Christopher-Hennings E.A. Nelson J.K. Nelson K.D. Rossow J.L. Shivers M.J. Yaeger C.C. Chase R.A. Garduno J.E. Collins D.A. Benfield Identification of porcine reproductive and respiratory syndrome virus in semen and tissues from vasectomized and nonvasectomized boars Vet. Pathol. 35 1998 260 267
9. L.A. Day Conformations of single-stranded DNA and coat protein in fd bacteriophage as revealed by ultraviolet absorption spectroscopy J. Mol. Biol. 39 1969 265 277
10. M. De Diego M.D. Laviada L. Enjuanes J.M. Escribano Epitope specificity of protective lactogenic immunity against swine transmissible gastroenteritis virus J. Virol. 66 1992 6502 6508
11. M. De Diego F. Rodriguez C. Alcaraz N. Gomez C. Alonso J.M. Escribano Characterization of the IgA and subclass IgG responses to neutralizing epitopes after infection of pregnant sows with the transmissible gastroenteritis virus or the antigenically related porcine respiratory coronavirus J. Gen. Virol. 75 10 1994 2585 2593
12. C. Dewey G. Charbonneau S. Carman A. Hamel G. Nayar R. Friendship K. Eernisse S. Swenson Lelystad-like strain of porcine reproductive and respiratory syndrome virus (PRRSV) identified in Canadian swine Can. Vet. J. 41 2000 493 494
13. H. Ernø E. Blom Mycoplasmosis: experimental seminal vesiculitis. Demonstration of locally occurring antibody Acta Vet. Scand. 14 1973 332 334
14. M.J. Francis G.Z. Hastings A.D. Syred B. McGinn F. Brown D.J. Rowlands Non-responsiveness to a foot-and-mouth disease virus peptide overcome by addition of foreign helper T-cell determinants Nature 330 1987 168 170
15. H. Fujioka S.N. Emancipator M. Aikawa D.S. Huang F. Blatnik T. Karban K. DeFife M.B. Mazanec Immunocytochemical colocalization of specific immunoglobulin A with sendai virus protein in infected polarized epithelium J. Exp. Med. 188 1998 1223 1229
16. Glossop, C., 1998. AI in pigs: the production of quality-assured, healthy semen. in press, 182–188.
17. C. Gradil C. Dubuc M.D. Eaglesome Porcine reproductive and respiratory syndrome virus: seminal transmission Vet. Rec. 138 1996 521 522
18. F. Haimovici K.H. Mayer D.J. Anderson Quantitation of HIV-1-specific IgG, IgA, and IgM antibodies in human genital tract secretions J. Acquir. Immune. Defic. Syndr. Hum. Retrovirol. 15 1997 185 191
19. G.R. Holyoak T.V. Little W.H. McCollam P.J. Timoney Relationship between onset of puberty and establishment of persistent infection with equine arteritis virus in the experimentally infected colt J. Comp. Pathol. 109 1993 29 46
20. V.S. Kiktenko N.G. Balashov V.N. Rodina Leptospirosis infection through insemination of animals J. Hy. Epidemiol. microbiol. Immunol. 20 1976 207 213
21. S.R. Lawson K.D. Rossow J.E. Collings D.A. Benfield R.R.R. Rowland Porcine reproductive and respiratory syndrome virus infection of gnotobiotic pigs: sites of virus replication and co-localization with MAC-387 staining at 21 days post-infection Virus Res. 51 1997 105 113
22. O. Legeay S. Bounaix M. Denis C. Arnauld E. Hutet R. Cariolet E. Albina A. Jestin Development of a RT-PCR test coupled with a microplate colorimetric assay for the detection of a swine Arterivirus (PRRSV) in boar semen J. Virol. Methods 68 1997 65 80
23. K.G. Madsen C.M. Hansen E.S. Madsen B. Strandbygaard A. Bøtner K.J. Sørensen Detection of porcine reproductive and respiratory syndrome virus of the American type in Danish swine herds Arch. Virol. 143 1998 1683 1700
24. P. Mauclere F. Damond C. Apetrei I. Loussert-Ajaka S. Souquiere L. Buzelay P. Dalbon M. Jolivet L.M. Mony F. Brun-Vezinet F. Simon F. Barin Synthetic peptide ELISAs for detection of and discrimination between group M and group O HIV type 1 infection AIDS Res. Hum. Retroviruses 13 1997 987 993
25. M.B. Mazanec C.S. Kaetzel M.E. Lamm D. Fletcher J.G. Nedrud Intracellular neutralization of virus by immunoglobulin A antibodies Proc. Natl. Acad. Sci. USA 89 1992 6901 6905
26. M.B. Mazanec C.L. Coudret D.R. Fletcher Intracellular neutralization of influenza virus by immunoglobulin A anti-hemagglutinin monoclonal antibodies J. Virol. 69 1995 1339 1343
27. W.H. McCollum T.V. Little P.J. Timoney T.W. Swerczek Resistance of castrated male horses to attempted establishment of the carrier state with equine arteritis virus J. Comp. Pathol. 111 1994 383 388
28. T.L. Nielsen J. Nielsen P. Have P. Baekbo J.R. Hoff A. Botner Examination of virus shedding in semen from vaccinated and from previously infected boars after experimental challenge with porcine reproductive and respiratory syndrome virus Vet. Microbiol. 54 1997 101 112
29. M.B. Oleksiewicz A. Botner K.G. Madsen T. Storgaard Sensitive detection and typing of porcine reproductive and respiratory syndrome virus by RT-PCR amplification of whole viral genes Vet. Microbiol. 64 1998 7 22
30. Oleksiewicz, M.B., Bøtner, A., Toft, P., Normann, P., Storgaard, T., 2001. Epitope mapping porcine reproductive and respiratory syndrome virus (PRRSV) by phage display: the nsp2 fragment of the replicase polyprotein contains a cluster of B-cell epitopes. In Press.
31. M. Philpott The dangers of disease transmission by artificial insemination and embryo transfer Br. Vet. J. 149 1993 339 369
32. C. Prieto P. Suarez J.M. Bautista R. Sanchez S.M. Rillo I. Simarro A. Solana J.M. Castro Semen changes in boars after experimental infection with porcine reproductive and respiratory syndrome virus Theriogenology 45 1996 383 395
33. C. Prieto P. Suarez I. Simarro C. Garcia S. Martin-Rillo J.M. Castro Insemination of susceptible and preimmunized gilts with boar semen containing porcine reproductive and respiratory syndrome virus Theriogenology 47 1997 647 654
34. K.D. Rossow D.A. Benfield S.M. Goyal E.A. Nelson H.J. Christopher J.E. Collins Chronological immunohistochemical detection and localization of porcine reproductive and respiratory syndrome virus in gnotobiotic pigs Vet. Pathol. 33 1996 551 556
35. L.J. Saif Mucosal immunity: an overview and studies of enteric and respiratory coronavirus infections in a swine model of enteric disease Vet. Immunol. Immunopathol. 54 1996 163 169
36. J.S. Salt The carrier state in foot and mouth disease — an immunological review Br. Vet. J. 149 1993 207 223
37. J. Shin J. Torrison C.S. Choi S.M. Gonzalez B. Crabo T.W. Molitor Monitoring of porcine reproductive and respiratory syndrome virus infection in boars Vet. Microbiol. 55 1997 337 346
38. J. Shin E.M. Bautista Y.B. Kang T.W. Molitor Quantitation of porcine reproductive and respiratory syndrome virus RNA in semen by single-tube reverse transcription-nested polymerase chain reaction J. Virol. Methods 72 1998 67 79
39. E.J. Snijder J.J.M. Meulenberg The molecular biology of arteriviruses J. Gen. Virol. 79 1998 961 979
40. J.H. Sur V.L. Cooper J.A. Galeota R.A. Hesse A.R. Doster F.A. Osorio In vivo detection of porcine reproductive and respiratory syndrome virus RNA by in situ hybridization at different times postinfection J. Clin. Microbiol. 34 1996 2280 2286
41. J.-H. Sur A.R. Doster J.S. Christian J.A. Galeota R.W. Wills J.J. Zimmerman F.A. Osorio Porcine reproductive and respiratory syndrome virus replicates in testicular germ cells, alters spermatogenesis, and induces germ cell death by apoptosis J. Virol. 71 1997 9170 9179
42. S.L. Swenson H.T. Hill J.J. Zimmerman L.E. Evans J.G. Landgraf R.W. Wills T.P. Sanderson M.J. McGinley A.K. Brevik D.K. Ciszewski Excretion of porcine reproductive and respiratory syndrome virus in semen after experimentally induced infection in boars J. Am. Vet. Med. Assoc. 204 1994 1943 1948
43. P. Valadon M.D. Scharff Enhancement of ELISAs for screening peptides in epitope phage display libraries J. Immunol. Methods 197 1996 171 179
44. D. Van Zaane M.M. Hulst Monoclonal antibodies against porcine immunoglobulin isotypes Vet. Immunol. Immunopathol. 16 1987 23 36
45. H. Wolff K. Mayer G. Seage J. Politch C.R. Horsburgh D. Anderson A comparison of HIV-1 antibody classes, titers, and specificities in paired semen and blood samples from HIV-1 seropositive men J. Acquir. Immune. Defic. Syndr. 5 1992 65 69
46. E.L. Woodbury A review of the possible mechanisms for the persistence of foot-and-mouth disease virus Epidemiol. Infect. 114 1995 1 13