Post-hypoxic magnesium decreases nuclear oxidative damage in the fetal guinea pig brain

Brain Research

Volumn 890, Issue 1, 2001, Pages 130-136

  Maulik, Dev ^a   Qayyum, Imran ^b   Powell, Saul R ^a   Karantza, Maria ^b   Prakash Mishra, Om ^b   Delivoria Papadopoulos, Maria ^b  

^a WINTHROP UNIVERSITY HOSPITAL   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Brain; DNA fragmentation; Fetus; Hypoxia; Magnesium

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM); ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; DNA; MAGNESIUM;

ANIMAL MODEL; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; CEREBRAL PALSY; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; FETUS; GUINEA PIG; LIPID PEROXIDATION; NONHUMAN; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; BRAIN; CALCIUM CHANNEL BLOCKERS; DNA FRAGMENTATION; FEMALE; FETUS; GUINEA PIGS; HYPOXIA, BRAIN; LIPID PEROXIDATION; MAGNESIUM SULFATE; NA(+)-K(+)-EXCHANGING ATPASE; OXIDATIVE STRESS; PREGNANCY;

EID: 0035951657     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)03153-X     Document Type: Article

References (44)

1. Alcohol intoxication results in rapid loss in free magnesium in brain and disturbances in brain bioenergetics: Relation to cerebrovasospasm, alcohol-induced strokes, and barbiturate anesthesia-induced deaths
2. Fractionation of nuclei from brain by zonal centrifugation and a study of the ribonucleic acid polymerase activity in the various classes of nuclei
3. Apoptosis - The cell's silent exit
4. 2+ alone
5. Experimental magnesium depletion in adult rabbits caused by blast overpressure
6. Apoptosis and programmed cell death: A role in cerebral ischemia
7. Magnesium deficiency in vitro enhances free radical-induced intracellular oxidation and cytotoxicity in endothelial cells
8. Fluorescent damage products of lipid peroxidation
9. Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death. Involvement of serine but not cysteine proteases
10. Apoptosis in perinatal hypoxic-ischaemic cerebral damage
11. Apoptosis in the brains of infants suffering intrauterine cerebral injury
12. Activation of a calcium magnesium independent endonuclease in human leukemic cell apoptosis
13. A simple method for the isolation and purification of total lipids from animal tissue
14. Magnesium reduces free radicals in an in vivo coronary occlusion-reperfusion model
15. Magnesium sulfate tocolysis and risk of neonatal death
16. RNA polymerase activity in various classes of nuclei from different regions of rat brain during postnatal development
17. Effects of magnesium and iron on lipid peroxidation in cultured hepatocytes
18. Fetal serum and amniotic fluid magnesium concentrations with maternal treatment
19. Transfer of maternally administered magnesium sulfate into the fetal compartment of the rat: Assessment of amniotic fluid, blood, and brain concentrations
20. Appearance of 1-2 Mbp giant DNA fragments as an early common response leading to cell death induced by various substances that cause oxidative stress
21. Active oxygen-mediated chromosomal 1-2 Mbp giant DNA fragmentation into internucleosomal DNA fragmentation in apoptosis of glioma cells induced by glutamate
22. Magnesium sulfate and cerebral palsy in premature infants
23. Magnesium-deficiency potentiates free radical production associated with postischemic injury to rat hearts: Vitamin E affords protection
24. Creatine phosphate
25. Calcium, free radicals and excitotoxins in neuronal apoptosis
26. Excitatory amino acids as a final common pathway for neurologic disorders
27. Protein measurement with the Folin phenol reagent
28. Neuroprotective effects of preischemia intra-arterial magnesium sulfate in reversible focal cerebral ischemia
29. Direct measurement of oxygen free radicals during in-utero hypoxia in the fetal guinea pig brain
30. Oxygen free radical generation during in-utero hypoxia in the fetal guinea pig brain: The effects of maturity and of magnesium sulfate administration
31. +-ATPase in developing fetal guinea pig brain and the effect of maternal hypoxia
32. Cellular mechanisms of hypoxic injury in the developing brain
33. Chronic alcohol exposure decreases brain intracellular free magnesium concentration in rats
34. Can magnesium sulfate reduce the risk of cerebral palsy in very low birthweight infants
35. Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes
36. Magnesium sulfate after transient hypoxia-ischemia fails to prevent delayed cerebral energy failure in the newborn piglet
37. Pretreatment with magnesium protects NMDA receptor in fetal guinea pig brain during hypoxia
38. The effect of magnesium on oxidative neuronal injury in vitro
39. Spin-trapping studies of hepatic free radicals formed following the acute administration of ethanol to rats: In vivo detection of 1-hydroxyethyl radicals with PBN
40. Pretreatment with magnesium sulfate protects against hypoxic-ischemic brain injury but post-asphyxial treatment worsens brain damage in seven-day-old rats
41. 2+ concentration after forebrain ischemia in the rat
42. Acute and prolonged alterations in brain free magnesium following fluid percussion-induced brain trauma in rats
43. Brain injury in the premature infant. Neuropathology, clinical aspects, pathogenesis, and prevention
44. Detection of free radicals during brain ischemia and reperfusion by spin trapping and microdialysis