Fas/FasL-independent activation-induced cell death of T lymphocytes from HIV-infected individuals occurs without DNA fragmentation

Cellular Immunology

Volumn 214, Issue 1, 2001, Pages 1-11

  Kottilil, S ^a   Bowmer, M I ^b   Trahey, J ^c   Howley, C ^c   Gamberg, J ^a   Grant, M D ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^b MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^c St John's Health Care Corporation   (Canada)

Author keywords

Antioxidants; Apoptosis; Ionomycin; Phorbol esters

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CALCIUM; CASPASE INHIBITOR; CHROMIUM 51; CYCLOHEXIMIDE; DNA FRAGMENT; FAS ANTIGEN; FAS LIGAND; IONOMYCIN; MONOCLONAL ANTIBODY CD3; PHORBOL 13 ACETATE 12 MYRISTATE; PROPIDIUM IODIDE; THIOUREA;

ARTICLE; CELL DEATH; CELL MEDIATED CYTOTOXICITY; CELL MEMBRANE; CELL NUCLEUS; CHROMOSOME; CONTROLLED STUDY; DNA DETERMINATION; ELECTRON MICROSCOPY; EXTRACELLULAR CALCIUM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; OXIDATIVE STRESS; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0035950976     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1006/cimm.2001.1876     Document Type: Article

References (20)

1. Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals
2. Programmed death of T cells in HIV- 1 infection
3. Programmed cell death in AIDS-related HIV and SIV infections
4. Programmed cell death AIDS: Significance of T-cell apoptosis in pathogenic and non-pathogenic primate lentiviral infections
5. Cross-linking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis
6. The cytopathic effect of HIV is associated with apoptosis
7. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV and SIV-infected lymph nodes
8. - antigenspecific T cellsto undergo apotosis by HIV-infected monocytes
9. Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for HIV pathogenesis
10. Fas and FasL in the homeostatic regulation of immune responses
11. The Fas receptor in HIV infection: Expression on peripheral blood lymphocytes and role in the depletion of T cells
12. Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals
13. - T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor
14. Cross-linking of Fas by antibodies to a peculiar domain of gp120 V3 loop can enhance T cell apeptosis in HIV-1-infected individuals
15. Rapid killing of human neutrophils by the potent activator phorbol 12-myristate 13-acetate (PMA) accompanied by changes different from typical apoptosis or necrosis
16. A novel type of cell death of lymphocytes induced by a monoclonal antibody without participation of complement
17. Death of bystander cells by a novel pathway involving early mitochondrial damage in human immunodeficiency virus-mediated lymphadenopathy
18. Rapid isolation of eukaryotic DNA
19. Regulation of CD4 and CD8 expression on mouse T cells
20. Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and BclX(L) levels in vivo