A role for the α113 (GH1) amino acid residue in the polymerization of sickle hemoglobin: Evaluation of its inhibitory strength and interaction linkage with two fiber contact sites (α16/23) located in the ab region of the α-chain

Journal of Biological Chemistry

Volumn 276, Issue 21, 2001, Pages 18209-18215

  Sivaram, Mylavarapu V S ^a   Sudha, Rajamani ^a   Roy, Rajendra P ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CRYSTAL STRUCTURE; HEMOGLOBIN; MUTAGENESIS; POLYMERIZATION;

MUTATIONS;

BIOCHEMISTRY;

HEMOGLOBIN; HEMOGLOBIN S;

ALPHA CHAIN; ALPHA HELIX; AMINO ACID METABOLISM; ANIMAL CELL; ARTICLE; CLUSTER ANALYSIS; HUMAN; HUMAN CELL; HYDROPHOBICITY; LINKAGE ANALYSIS; MOLECULAR INTERACTION; NONHUMAN; POINT MUTATION; POLYMERIZATION; PRIORITY JOURNAL; SICKLE CELL; SICKLE CELL ANEMIA; SITE DIRECTED MUTAGENESIS; SOLUBILITY; CHEMISTRY; DIMERIZATION; GENETICS; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

DIMERIZATION; HEMOGLOBIN, SICKLE; HUMANS; POINT MUTATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035947665     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101788200     Document Type: Article

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