Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors

Biochemical Journal

Volumn 313, Issue 3, 1996, Pages 951-956

  Serveau, Carole ^a   Lalmanach, Gilles ^a   Juliano, Maria A ^b   Scharfstein, Julio ^c   Juliano, Luiz ^b   Gauthier, Francis ^a  

^a UNIVERSITÉ DE TOURS   (France)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CATHEPSIN L; CRUZIPAIN; CYSTATIN; CYSTEINE PROTEINASE; KININOGEN; LYSOSOME ENZYME; PROTEINASE INHIBITOR;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; ENZYME INHIBITION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; ANIMALS; CHICKENS; CYSTATINS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; FLUORESCENT DYES; HYDROLYSIS; KINETICS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; RATS; SUBSTRATE SPECIFICITY; TRYPANOSOMA CRUZI;

EID: 0030034874     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3130951     Document Type: Article

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