Candelalides A-C: Novel diterpenoid pyrones from fermentations of Sesquicillium candelabrum as blockers of the voltage-gated potassium channel Kv1.3

Organic Letters

Volumn 3, Issue 2, 2001, Pages 247-250

  Singh, Sheo B ^a   Zink, Deborah L ^a   Dombrowski, Anne W ^a   Dezeny, Gabe ^a   Bills, Gerald F ^a   Felix, John P ^a   Slaughter, Robert S ^a   Goetz, Michael A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANDELALIDE A; CANDELALIDE B; CANDELALIDE C; DITERPENE; IMMUNOSUPPRESSIVE AGENT; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KV1.1; PYRONE DERIVATIVE; RECOMBINANT PROTEIN; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL; ARTICLE; ASCOMYCETES; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL; CONFORMATION; DRUG ANTAGONISM; FERMENTATION; GROWTH, DEVELOPMENT AND AGING; HAMSTER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS;

ANIMALS; CHO CELLS; CRICETINAE; DITERPENES; FERMENTATION; HYPOCREALES; IMMUNOSUPPRESSIVE AGENTS; KV1.1 POTASSIUM CHANNEL; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PYRONES; RECOMBINANT PROTEINS;

EID: 0035945743     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol006891x     Document Type: Article

References (13)

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