Neuroprotective actions in vivo and electrophysiological actions in vitro of 202W92

Brain Research

Volumn 919, Issue 2, 2001, Pages 259-268

  Caputi, L ^a   Hainsworth, A H ^b   Lavaroni, F ^c   Leach, M J ^d   McNaughton, N C L ^e   Mercuri, N B ^a   Randall, A D ^e   Spadoni, F ^c   Swan, J H ^d   Stefani, A ^c  

^a IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^b DE MONTFORT UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d UNIVERSITY OF GREENWICH   (United Kingdom)

^e GLAXOSMITHKLINE   (United Kingdom)

Author keywords

202W92; Brain ischemia; Neuroprotective; Sodium channel pharmacology

Indexed keywords

2,4 DIAMINO 6 (FLUROMETHYL) 5 (2,3,5 TRICHLOROPHENYL)PYRIMIDINE; 202W92; 4 AMINOPYRIDINE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; NEUROPROTECTIVE AGENT; NIFEDIPINE; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN CELL; BRAIN CORTEX; BRAIN ELECTROPHYSIOLOGY; BRAIN ISCHEMIA; CALCIUM CURRENT; CELL STRAIN GH3; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG SENSITIVITY; DRUG STRUCTURE; EXCITATORY POSTSYNAPTIC POTENTIAL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; RAT; SYNAPTIC TRANSMISSION;

ANIMALS; BRAIN ISCHEMIA; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CELLS, CULTURED; CEREBRAL INFARCTION; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY POSTSYNAPTIC POTENTIALS; GLUTAMIC ACID; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MEMBRANE POTENTIALS; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; PATCH-CLAMP TECHNIQUES; PYRIMIDINES; RATS; RATS, INBRED F344; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; SUBSTANTIA NIGRA; SYNAPTIC TRANSMISSION; TELENCEPHALON;

EID: 0035940739     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)03029-3     Document Type: Article

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