1,2,5-Thiadiazole derivatives are potent and selective ligands at human 5-HT1A receptors

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 8, 2001, Pages 1069-1071

  Sabb, Annmarie L ^a   Vogel, Robert L ^a   Kelly, Michael G ^b   Palmer, Yvette ^a   Smith, Deborah L ^a   Andree, Terrance H ^a   Schechter, Lee E ^a  

^a PFIZER INC   (United States)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,5 THIADIAZOLE DERIVATIVE; BUSPIRONE; DIZOCILPINE; DOPAMINE RECEPTOR; FLESINOXAN; LIGAND; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; THIADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; ENANTIOMER;

AMINO ACIDS; ANIMALS; CHO CELLS; CRICETINAE; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; PIPERAZINES; PYRIDINES; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, DOPAMINE; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; THIADIAZOLES;

EID: 0035938409     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00151-2     Document Type: Article

References (7)