New generation dopaminergic agents. 7. Heterocyclic bioisosteres that exploit the 3-OH-phenoxyethylamine D2 template

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 17, 1999, Pages 2593-2598

  Mewshaw, Richard E ^a   Nelson, James A ^a   Shah, Uresh S ^a   Shi, Xiaojie ^a   Mazandarani, Hossein ^a   Coupet, Joseph ^a   Marquis, Karen ^a   Brennan, Julie A ^a   Andree, Terrance H ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; DOPAMINE 2 RECEPTOR STIMULATING AGENT; HETEROCYCLIC COMPOUND;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN CELL; DOPAMINERGIC ACTIVITY; DRUG SYNTHESIS; MOUSE; NONHUMAN; RAT; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; BENZIMIDAZOLES; DOPAMINE AGENTS; MICE; MOTOR ACTIVITY; RECEPTORS, DOPAMINE D2;

EID: 0033530092     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00434-5     Document Type: Article

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11. i values are the means of n = 2-3 experiments run at six different concentrations. Each experiment was carried out in triplicate. 95% confidence limits were generally ±15% of the mean value