Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 20, 2001, Pages 2683-2686

  Webber, Stephen E ^a,b   Marakovits, Joseph T ^a   Dragovich, Peter S ^a   Prins, Thomas J ^a   Zhou, Ru ^a   Fuhrman, Shella A ^a   Patick, Amy K ^a   Matthews, David A ^a   Lee, Caroline A ^a   Srinivasan, Babu ^a   Moran, Terry ^a   Ford, Clifford E ^a   Brothers, Mary A ^a   Harr, James E V ^a   Meador III, James W ^a   Ferre, Rose Ann ^a   Worland, Stephen T ^a  

^a PFIZER INC   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DEPSIPEPTIDE; HUMAN RHINOVIRUS 3C PROTEASE INHIBITOR DERIVATIVE; PROTEINASE INHIBITOR; TRIPEPTIDE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN RHINOVIRUS; VIRUS INHIBITION;

ANTIVIRAL AGENTS; CYSTEINE ENDOPEPTIDASES; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; PEPTIDES; PROTEASE INHIBITORS; RHINOVIRUS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL PROTEINS;

EID: 0035935181     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00542-X     Document Type: Article

References (23)