Schwann cell apoptosis in experimental autoimmune neuritis of the Lewis rat and the functional role of tumor necrosis factor-α

Neuroscience Letters

Volumn 306, Issue 1-2, 2001, Pages 77-80

  Weishaupt, Andreas ^a   Brück, Wolfgang ^b   Hartung, Thomas ^c   Toyka, Klaus V ^a   Gold, Ralf ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

Apoptosis; Experimental autoimmune neuritis; Guillain Barr syndrome; Immunotherapy; In situ tailing; Peripheral nervous system; Schwann cells; T lymphocytes

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; APOPTOSIS; ARTICLE; AUTOIMMUNITY; CELL FATE; CONTROLLED STUDY; DISEASE COURSE; EXPERIMENTAL INFECTION; FEMALE; NERVE REGENERATION; NEURITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; REMYELINIZATION; T LYMPHOCYTE;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES; APOPTOSIS; FEMALE; GUILLAIN-BARRE SYNDROME; IMMUNOTHERAPY; MYELIN P2 PROTEIN; NEURITIS, AUTOIMMUNE, EXPERIMENTAL; PERIPHERAL NERVES; RATS; RATS, INBRED LEW; SCHWANN CELLS; SCIATIC NERVE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035933644     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)01877-8     Document Type: Article

References (23)

1. Transducers of life and death: TNF receptor superfamily and associated proteins
2. Lipopolysaccharide-induced interleukin-10 in mice: Role of endogenous tumor necrosis factor-α
3. Induction of experimental allergic neuritis with a peptide from myelin P2 basic protein
4. Schwann cell undergoes apoptosis during experimental allergic neuritis (EAN)
5. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation technique
6. Synergistic effect of IFN-gamma and TNF-α on expression of immune molecules and antigen presentation by Schwann cells
7. Local immune responses in the peripheral nervous system
8. Endotoxin-inducible cytotoxicity in liver cell cultures-I
9. A permanent rat T cell line that mediates experimental allergic neuritis in the Lewis rat in vivo
10. Upregulation of intracellular adhesion molecule-1 (ICAM-1) on rat Schwann cells in vitro: Comparison of interferon-γ, tumor necrosis factor-α and interleukin-1
11. The role of cytokines in Schwann cell damage, protection and repair
12. Human alpha tumor necrosis factor does not damage cultures containing rat Schwann cells and sensory neurons
13. T-cell apoptosis in situ in experimental autoimmune encephalomyelitis (EAE) following methylprednisolone (MP) pulse therapy: Possible implications for therapy of relapses in multiple sclerosis (MS)
14. TNF-α and TGF-α act synergistically to kill Schwann cells
15. Painful mononeuropathy in C57BL/Wld mice with delayed wallerian degeneration: Differential effects of cytokine production and nerve regeneration on thermal and mechanical hypersensitivity
16. Heterogeneity of T-cell receptor usage in experimental autoimmune neuritis in the Lewis rat
17. Schwann cells produce tumor necrosis factor alpha expression in injured and non-injured nerves
18. T cell antigenic and neuritogenic activity of recombinant human peripheral myelin P2 protein
19. Antigen therapy eliminates T cell inflammation by apoptosis: Effective treatment of experimental autoimmune neuritis with recombinant myelin protein P2
20. Role of TNF-α in high-dose antigen therapy in experimental autoimmune neuritis: Inhibition of TNF-α by neutralizing antibodies reduces T-cell apoptosis and prevents liver necrosis
21. Molecular mechanisms of high-dose antigen therapy in experimental autoimmune encephalomyelitis: Rapid induction of Th1-type cytokines and inducible nitric oxide synthase
22. Regulation of Fas and FasL expression on rat Schwann cells
23. Intravenous glucocorticosteroid treatment augments apoptosis of inflammatory T cells in experimental autoimmune neuritis (EAN) of the Lewis rat