The pathology of familial breast cancer: Histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2

Clinical Cancer Research

Volumn 6, Issue 3, 2000, Pages 782-789

  Lakhani, Sunil R ^a   Gusterson, Barry A ^b   Jacquemier, Jocelyne ^r   Sloane, John P ^ac   Anderson, Thomas J ^q   Van De Vijver, Marc J ^y   Venter, Deon ^s,t   Freeman, Alex ^a   Antoniou, Antonios ^c   McGuffog, Lesley ^h   Smyth, Elizabeth ^m   Steel, C Michael ^v   Haites, Neva ^j   Scott, Rodney J ^k   Goldgar, David ^g   Neuhausen, Susan ^p   Daly, Peter A ^w   Ormiston, Wilma ^w   McManus, Ross ^w   Scherneck, Siegfried ^z   Ponder, Bruce A J ⁱ   Futreal, P Andrew ^ab   Peto, Julian ^b   Stoppa Lyonnet, Dominique ^x   Bignon, Yves Jean ^l   Struewing, Jeffery P ^ac   Bishop, D Timothy ^d   Klijn, J G M ^aa   Devilee, Peter ^f   Cornelisse, Cees J ^f   Lasset, Christine ^u   Lenoir, Gilbert ^g   Barkardottir, Rosa Bjork ^e   Egilsson, Valgardur ^e   Hamann, Ute ⁿ   Chang Claude, Jenny ⁿ   Sobol, Hagay ^r   Weber, Barbara ^o   Easton, Douglas F ^h   Stratton, Michael R ^b   more..

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^e LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^f LEIDEN UNIVERSITY   (Netherlands)

^g INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^h UNIVERSITY OF CAMBRIDGE   (United Kingdom)

ⁱ ADDENBROOKE S HOSPITAL   (United Kingdom)

^j UNIVERSITY OF ABERDEEN   (United Kingdom)

^k JOHN HUNTER HOSPITAL   (Australia)

^l CENTRE JEAN PERRIN   (France)

^m WESTERN GENERAL HOSPITAL   (United Kingdom)

ⁿ GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^o UNIVERSITY OF PENNSYLVANIA   (United States)

^p UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^q UNIVERSITY OF EDINBURGH   (United Kingdom)

^r INSTITUT PAOLI CALMETTES   (France)

^s PETER MACCALLUM CANCER CENTRE   (Australia)

^t UNIVERSITY OF MELBOURNE   (Australia)

^u CENTRE LÉON BÉRARD   (France)

^v UNIVERSITY OF ST ANDREWS   (United Kingdom)

^w TRINITY COLLEGE DUBLIN   (Ireland)

^x INSTITUT CURIE   (France)

^y NETHERLANDS CANCER INSTITUTE   (Netherlands)

^z MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^aa ERASMUS MEDICAL CENTER   (Netherlands)

^ab DUKE UNIVERSITY   (United States)

^ac NONE

more..

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ARTICLE; BREAST CARCINOMA; CANCER GRADING; CANCER INVASION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; FAMILIAL CANCER; FEMALE; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LYMPHOCYTIC INFILTRATION; MITOSIS INDEX; PRIORITY JOURNAL; TUMOR NECROSIS;

BRCA2 PROTEIN; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, LOBULAR; CARCINOMA, MEDULLARY; FAMILY HEALTH; FEMALE; GENES, BRCA1; HUMANS; LYMPHOCYTES, TUMOR-INFILTRATING; MITOTIC INDEX; MUTATION; NEOPLASM PROTEINS; TRANSCRIPTION FACTORS;

EID: 12944286550     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Lakhani, S. R., Easton, D. F., Stratton, M. R., and the Breast Cancer Linkage Consortium. Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases. Lancet, 349: 1505-1510, 1997.
2. Lakhani, S. R., Jacquemier, J., Sloane, J. P., Gusterson, B. A., Anderson, T. J., van de Vijver, M. J., Farid, L. M., Venter, D., Antoniou, A., Storfer-Isser, A., Smyth, E., Steel, C. M., Haites, N., Scott, R. J., Goldgar, D., Neuhausen, S., Daly, P. A., Ormiston, W., McManus, R., Scherneck, S., Ponder, B. A., Ford, D., Peto, J., Stoppa-Lyonnet, D., Bignon, Y. J., Streuwing, J. P., Spurr, N. K., Bishop, D. T., Klijn, J. G. M., Devilee, P., Cornelisse, C. J., Lasset, C., Lenoir, G. R., Barkardottir, R. B., Egilsson, V., Hamann, U., Chang-Claude, J., Sobol, H., Weber, B., Stratton, M. R., and Easton, D. F. Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations. J. Natl. Cancer Inst., 90: 1138-1145, 1998.
3. Karp, S. E., Tonin, P. N., Begin, L. R., Martinez, J. J., Zhang, J. C., Pollak, M. N., and Foulkes, W. D. Influence of BRCA1 mutations on nuclear grade and estrogen receptor status of breast carcinoma in Ashkenazi Jewish women. Cancer (Phila.), 80: 435-441, 1997.
4. Eisinger, F., Stoppa-Lyonnet, D., Longy, M., Kerangueven, F., Noguchi, T., Bailly, C., Vincent-Salomon, A., Jacquemier, J., Birnbaum, D., and Sobol, H. Germ-line mutation at BRCA1 affects the histoprognostic grade in hereditary breast cancer. Cancer Res., 56: 471-474, 1996.
5. Johannsson, O. T., Idvall, I., Anderson, C., Borg, A., Barkardottir, R. B., Egilsson, V., and Olsson, H. Tumour biological features of BRCA1-induced breast and ovarian cancer. Eur. J. Cancer, 33: 362-371, 1997.
6. Robson, M., Gilewski, T., Haas, B., Levin, D., Borgen, P., Rajan, P., Hirschaut, Y., Pressman, P., Rosen, P. P., Lesser, M. L., Norton, L., and Offit, K. BRCA-associated breast cancer in young women. J. Clin. Oncol., 16: 1642-1649, 1998.
7. Armes, J. E., Egan, A. J., Southey, M. C., Dite, G. S., McCredie, M. R., Giles, G. G., Hopper, J. L., and Venter, D. J. The histologic phenotypes of breast carcinoma occurring before age 40 years in women with and without BRCA1 or BRCA2 germline mutations: a population-based study. Cancer (Phila.), 83: 2335-2345, 1998.
8. Lynch, B. J., Holden, J. A., Buys, S. S., Neuhausen, S. L., and Gaffney, D. K. Pathobiologic characteristics of hereditary breast cancer. Hum. Pathol., 29: 1140-1144, 1998.
9. Marcus, J. N., Watson, P., Page, D. L., Narod, S. A., Lenoir, G. M., Tonin, P., Linder-Stephenson, L., Salerno, G., Conway, T. A., and Lynch, H. T. Hereditary breast cancer: pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage. Cancer (Phila.), 77: 697-709, 1996.
10. Marcus, J. N., Watson, P., Page, D. L., Narod, S. A., Tonin, P., Lenoir, G. M., Serova, O., and Lynch, H. T. BRCA2 hereditary breast cancer pathophenotype. Breast Cancer Res. Treat., 44: 275-277, 1997.
11. Agnarsson, B. A., Jonasson, J. G., Bjornsdottir, I. B., Barkardottir, R. B., Egilsson, V., and Sigurdsson, H. Inherited BRCA2 mutation associated with high grade breast cancer. Breast Cancer Res. Treat., 47: 121-127, 1998.
12. Ford, D., Easton, D. F., Stratton, M. R., Narod, S., Goldgar, D., Devilee, P., Bishop, D. T., Weber, B., Lenoir, G., Chang-Claude, J., Sobol, H., Teare, M. D., Streuwing, J., Arason, A., Scherneck, S., Peto, J., Rebbeck, T. R., Tonin, P., Neuhausen, S., Barkadottir, R., Eyfjord, J., Lynch, H., Ponder, B. A. J., Gayther, S. A., Birch, J. M., Lindblom, A., Stoppa-Lyonnet, D., Bignon, Y., Borg, A., Hamann, U., Haites, N., Scott, R. J., Maugard, C. M., Vasen, H., Seitz, S., Cannon-Albright, L. A., Schofield, A., Hedman, M. Z., and the Breast Cancer Linkage Consortium Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in Breast Cancer Families. Am. J. Hum. Genet., 62: 676-689, 1998.
13. Peto, J., Collins, N., Barfoot, R., Seal, S., Warren, W., Rahman, N., Easton, D. F., Evans, C., Deacon, J., and Stratton, M. R. Prevalence of BRCA1 and BRCA2 gene mutations in patients with early-onset breast cancer. J. Natl. Cancer Inst., 91: 943-949, 1999.
14. Liaw, D., Marsh, D. J., Li, J., Dahia, P. L., Wang, S. I., Zheng, Z., Bose, S., Call, K. M., Tsou, H. C., Peacocke, M., Eng, C., and Parsons, R. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet., 16: 64-67, 1997.
15. Birch, J. M., Hartley, A. L., Tricker, K. J., Prosser, J., Condie, A., Kelsey, A. M., Harris, M., Jones, P. H., Binchy, A., and Crowther, D. Prevalence and diversity of constitutional mutations in the p53 gene among 21 Li-Fraumeni families. Cancer Res., 54: 1298-1304, 1994.
16. Swift, M., Morrell, D., Massey, R. B., and Chase, C. L. Incidence of cancer in 161 families affected by ataxia-telangiectasia. N. Engl. J. Med., 325: 1831-1836, 1991.
17. Zuppan, P., Hall, J. M., Lee, M. K., Ponglikitmongkol, M., and King, M. C. Possible linkage of the estrogen receptor gene to breast cancer in a family with late-onset disease. Am. J. Hum. Genet., 48: 1065-1068, 1991.
18. Kerangueven, F., Essioux, L., Dib, A., Noguchi, T., Allione, F., Geneix, J., Longy, M., Lidereau, R., Eisinger, F., Pebusque, M-J., Jacquemier, J., Bonaiti-Pellie, C., Sobol, H., and Birnbaum, D. Loss of heterozygosity and linkage analysis in breast carcinoma: indication for a putative third susceptibility gene on the short arm of chromosome 8. Oncogene, 10: 1023-1026, 1995.
19. National Coordinating Group for Breast Screening Pathology. Pathology reporting in breast cancer screening. NHSBSP Publication No. 3, Ed. 2. Sheffield: NHSBSP, 1995.
20. Huber, P. J. The behaviour of maximum likelihood estimates under nonstandard conditions. Proc. Berkeley Symp. Math. Stat. Probab., 1: 221-233, 1967.
21. Efron, B., and Tibishirani, R. An Introduction to the Bootstrap. New York: Chapman and Hall, 1993.
22. Breslow, N. E., and Day, N. E. Statistical methods in cancer research. Volume I-The Analysis of Case-Control Studies. Int. Agency Res. Cancer Sci. Publ., 335-338, 1980.
23. Peto, J., Easton, D. F., Matthews, F. E., Ford, D., and Swerdlow, A. J. Cancer mortality in relatives of women with breast cancer: the OPCS study. Int. J. Cancer, 65: 275-283, 1996.
24. Cannon-Albright, L. A., Thomas, A., Goldgar, D. E., Gholami, K., Rowe, K., Jacobsen, M., McWhorter, W. P., and Skolnick, M. H. Familiality of cancer in Utah. Cancer Res., 54: 2378-2385, 1994.
25. Rosen, P. P., Lesser, M. L., Senie, R. T., and Kinne, D. W. Epidemiology of breast carcinoma III: relationship of family history to tumor type. Cancer (Phila.), 50: 171-179, 1982.
26. Erdreich, L. S., Asal, N. R., and Hoge, A. F. Morphologic types of breast cancer: age, bilaterality, and family history. South. Med. J., 73: 28-32, 1980.
27. Claus, E. B., Risch, N., Thompson, W. D., and Carter, D. Relationship between breast histopathology and family history of breast cancer. Cancer (Phila.), 71: 147-153, 1993.