Stabilization of a tetrameric enzyme (α-amino acid ester hydrolase from Acetobacter turbidans) enables a very improved performance of ampicillin synthesis

Journal of Molecular Catalysis - B Enzymatic

Volumn 11, Issue 4-6, 2001, Pages 633-638

  Fernandez Lafuente, Roberto ^a   Hernández Jústiz, Odette ^a   Mateo, Cesar ^a   Terreni, Marco ^a   Alonso, Jorge ^b   Garcia López, Jose L ^b   Moreno, Miguel A ^c   Guisan, Jose M ^a  

^a INSTITUTO DE CATÁLISIS Y PETROLEOQUÍMICA   (Spain)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^c Avenida de Antibioóticos 59 61   (Spain)

Author keywords

Enzymatic synthesis of ampicillin; Enzyme specificity; Stabilization of multimeric enzymes; Stereospecific synthesis

Indexed keywords

ACID HYDROLASE; AMPICILLIN; PENICILLIN AMIDASE;

ACETOBACTER; BIOCATALYST; CONFERENCE PAPER; DRUG SYNTHESIS; ENANTIOMER; ENZYME IMMOBILIZATION; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME STRUCTURE; ESCHERICHIA COLI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTEIN QUATERNARY STRUCTURE;

EID: 0035931487     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1381-1177(00)00065-5     Document Type: Conference Paper

References (13)

1. Stabilization of immobilized enzymes by chemical modification with polyfunctional macromolecules