CYP1A2 and clearance of clozapine: An aid in dose determination;CYP1A2 en de klaring van clozapine: Hulpmiddel ter bepaling van de dosis

Pharmaceutisch Weekblad

Volumn 136, Issue 38, 2001, Pages 1439-1442

  Dorhout Doude van Troostwijk, L J A E ^a   Koopmans, R P ^a   Vermeulen, H D B ^a   Guchelaar, H J ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; CLOZAPINE N OXIDE; CYTOCHROME P450 1A2; NORCLOZAPINE;

ARTICLE; DOSE CALCULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG METABOLISM; HUMAN; PSYCHOSIS;

EID: 0035929384     PISSN: 00316911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Clozapine. A novel antipsychotic agent
2. Will routine therapeutic drug monitoring have a place in clozapine therapy?
3. Pharmacokinetic interactions involving clozapine
4. Therapeutic drug monitoring of clozapine treatment. Therapeutic threshold value for serum clozapine concentrations
5. The use of caffeine for enzyme assays: A critical appraisal
6. Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva
7. Some suggestions for measuring predictive performance