Cytokine mRNA expression in mouse colon: IL-15 mRNA is overexpressed and is highly sensitive to a fibre-like dietary component (short-chain fructo-oligosaccharides) in an Apc gene manner

Cytokine

Volumn 14, Issue 4, 2001, Pages 243-246

  Bassonga, Euphémie ^a   Forest, Virginie ^a   Pierre, Fabrice ^a   Bornet, Francis ^b   Perrin, Pascale ^a   Meflah, Khaled ^a   Menanteau, Jean ^a  

^a INSTITUT DE BIOLOGIE   (France)

^b Eridania Beghin Say   (Belgium)

Author keywords

Cancer; Colon; Fructo oligosaccharides; IL 15; Min mouse

Indexed keywords

CYTOKINE; FRUCTOSE OLIGOSACCHARIDE; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIETARY FIBER; FERMENTATION; GENE OVEREXPRESSION; IMMUNOSURVEILLANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RIBONUCLEASE PROTECTION ASSAY; TUMOR SUPPRESSOR GENE;

EID: 0035926312     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2001.0872     Document Type: Article

References (15)

1. Only fibres promoting a stable butyrate-producting colonic ecosystem decrease the rate of aberrant crypt foci in rats
2. Effects of fructo-oligosaccharides ingestion on fecal bifidobacteria and selected metabolic indexes of colon carcinogenesis in healthy humans
3. Short-chain fructo-oligosaccharides reduce the occurrence of colon tumors and develop gut-associated lymphoid tissue in Min mice
4. Dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
5. T cell status influences colon tumor occurrence in Min mice fed short chain fructo-oligosaccharides as a diet supplement
6. Homeostatic regulation of intestinal epithelia by intraepithelial γδ T cells
7. The interaction of intestinal epithelial cells and intraepithelial lymphocytes in host defense
8. Intestinal epithelial cells both express and respond to interleukin 15
9. IL-15: A pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels
10. Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo
11. Interleukin-15 preferentially promotes the growth of intestinal intraepithelial lymphocytes bearing γδ T cell receptor in mice
12. Interleukin 15 is a potent stimulant of intraepithelial lymphocytes
13. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
14. Gene transfer of a secretable form of IL-15 in murine adenocarcinoma cells: Effects on tumorigenicity, metastatic potential and immune response
15. Transduction of murine colon carcinoma cells with interleukin 15 gene induces antitumor effects in immunocompetent and immunocompromised hosts