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Volumn 209, Issue 4, 2001, Pages 497-502

A mathematical model for experimental gene evolution

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GENE LIBRARY; GENE MUTATION; MATHEMATICAL MODEL; MOLECULAR CLONING; MOLECULAR EVOLUTION; MUTAGENESIS; MUTATION RATE; PRIORITY JOURNAL;

EID: 0035925920     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.2001.2286     Document Type: Article
Times cited : (6)

References (17)
  • 2
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    • Evaluation of loss and change of specificity resulting from random mutagenesis of an antibody VH region
    • (1995) J. Immunol. , vol.155 , pp. 5647-5654
    • Casson, L.P.1    Manser, T.2
  • 6
    • 0002829697 scopus 로고
    • Optimum mutation rate and degree of dominance as determined by the principle of minimum genetic load
    • (1960) J. Genetics , vol.57 , pp. 21-34
    • Kimura, M.1
  • 7
    • 0017368336 scopus 로고
    • Preponderance of synonymous changes as evidence for the neutral theory of molecular evolution
    • (1977) Nature , vol.267 , pp. 275-276
    • Kimura, M.1
  • 10
    • 0019134329 scopus 로고
    • Molecular evolution of mRNA: A method for estimating evolutionary rates of synonymous and amino acid substitutions from homologous nucleotide sequences and its application
    • (1980) J. Mol. Evol. , vol.16 , pp. 23-36
    • Miyata, T.1    Yasunaga, T.2
  • 14
    • 0028050350 scopus 로고
    • Rapid evolution of a protein in vitro by DNA shuffling
    • (1994) Nature , vol.370 , pp. 389-391
    • Stemmer, W.P.1
  • 16
    • 0033555718 scopus 로고    scopus 로고
    • The effect of high-frequency random mutagenesis on in vitro protein evolution: A study on TEM-1 beta-lactamase
    • (1999) J. Mol. Biol. , vol.285 , pp. 775-783
    • Zaccolo, M.1    Gherardi, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.