Stabilization of a recombinant Fv fragment by base-loop interconnection and V(H)-V(L) permutation

Journal of Molecular Biology

Volumn 268, Issue 1, 1997, Pages 107-117

  Brinkmann, Ulrich ^a   Di Carlo, Angelina ^a   Vasmatzis, George ^a   Kurochkina, Natalya ^a   Beers, Richard ^a   Lee, Byungkook ^a   Pastan, Ira ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Anti Tac; Antibody engineering; Cancer therapy; dsFv; scFv

Indexed keywords

IMMUNOGLOBULIN FRAGMENT; IMMUNOTOXIN; INTERLEUKIN 2 RECEPTOR ANTIBODY; PSEUDOMONAS EXOTOXIN; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIBODY STRUCTURE; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL INCLUSION; CONTROLLED STUDY; CYTOTOXICITY; IMMUNOGLOBULIN VARIABLE REGION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY;

EID: 0031586001     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0850     Document Type: Article

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