Assigning the positional identity of spinal motor neurons: Rostrocaudal patterning of Hox-c expression by FGFs, Gdf11, and retinoids

Neuron

Volumn 32, Issue 6, 2001, Pages 997-1012

  Liu, Jeh Ping ^a,b   Laufer, Ed ^a   Jessell, Thomas M ^a  

^a Columbia University ^*  (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; PROTEIN; PROTEIN HOX C; RETINOID; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL FATE; CHICK EMBRYO; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; EMBRYONIC STRUCTURES; GENE EXPRESSION REGULATION; MESODERM; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUAIL; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD MOTONEURON;

EID: 0035924596     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(01)00544-X     Document Type: Article

References (68)

1. Homeotic transformation of rhombomere identity after localized Hoxb1 misexpression
2. Multiple phases of expression and regulation of mouse Hoxc8 during early embryogenesis
3. Differential distribution of retinoic acid synthesis in the chicken embryo as determined by immunolocalization of the retinoic acid synthetic enzyme, RALDH-2
4. Specification of neuronal fates in the ventral neural tube
5. Targeted disruption of Hoxd-10 affects mouse hindlimb development
6. Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases
7. The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo
8. Targeted disruption of Hoxd9 and Hoxd10 alters locomotor behavior, vertebral identity, and peripheral nervous system development
9. The control of R-C pattern in the developing spinal cord: Specification of MN subtype identity is initiated by signals from paraxial mesoderm
10. Two critical periods of Sonic Hedgehog signaling required for the specification of MN identity
11. Segmental patterning of rat and chicken sympathetic preganglionic neurons: Correlation between soma position and axon projection pathway
12. A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos
13. Retinoid signalling and hindbrain patterning
14. Role of Hoxa-2 in axon pathfinding and rostral hindbrain patterning
15. Initiation of rhombomeric Hoxb4 expression requires induction by somites and a retinoid pathway
16. Hox gene induction in the neural tube depends on three parameters: Competence, signal supply and paralogue group
17. A series of normal stages in the development of the chick embryo
18. Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4
19. Organization of motor pools in the chick lumbar lateral motor column
20. Motoneuron histogenesis and the development of limb innervation
21. An autoradiographic study of the formation of the lateral motor column in the chick embryo
22. Regulation of Hox gene expression and posterior development by the Xenopus caudal homologue Xcad3
23. Reprogramming Hox expression in the vertebrate hindbrain: Influence of paraxial mesoderm and rhombomere transposition
24. Neuronal specification in the spinal cord: Inductive signals and transcriptional codes
25. Specification of distinct MN identities by the singular activities of individual Hox genes
26. Spinal cord neuronal precursors generate multiple neuronal phenotypes in culture
27. Coordinate roles for LIM homeobox genes in directing the D-V trajectory of motor axons in the vertebrate limb
28. Hensen's node induces neural tissue in Xenopus ectoderm. Implications for the action of the organizer in neural induction
29. Hoxd10 induction and regionalization in the developing lumbosacral spinal cord
30. The development of motor projection patterns in the chick hind limb
31. The distribution of motoneurones supplying chick hind limb muscles
32. The acquisition of motoneuron subtype identity and motor circuit formation
33. Topographic mapping of motor pools onto skeletal muscles
34. The specification of dorsal cell fates in the vertebrate central nervous system
35. Regulation of myostatin activity and muscle growth
36. Regulation of the neural patterning activity of sonic hedgehog by secreted BMP inhibitors expressed by notochord and somites
37. Functionally related MN pool and muscle sensory afferent subtypes defined by coordinate ETS gene expression
38. A role for rhoB in the delamination of neural crest cells from the dorsal neural tube
39. Patterning the vertebrate neuraxis
40. The distribution of endogenous retinoic acid in the chick embryo: Implications for developmental mechanisms
41. Multiple roles for FGF-3 during cranial neural development in the chicken
42. A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth
43. The chicken caudal genes establish an anterior-posterior gradient by partially overlapping temporal and spatial patterns of expression
44. FGF receptor signalling is required to maintain neural progenitors during Hensen's node progression
45. A critical period for the specification of motor pools in the chick lumbosacral spinal cord
46. Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite
47. Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11
48. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
49. Convergent inductive signals specify midbrain, hindbrain, and spinal cord identity in gastrula stage chick embryos
50. Expression of growth/differentiation factor 11, a new member of the BMP/TGFbeta superfamily during mouse embryogenesis
51. Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development
52. Retinoic acid synthesis and hindbrain patterning in the mouse embryo
53. Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse
54. The role of Sonic hedgehog in neural tube patterning
55. eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus
56. Nucleo-cytoplasmic translocation and secretion of fibroblast growth factor-2 during avian gastrulation
57. Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding
58. Morphological and mapping studies of the paranodal and postnodal levels of the neural plate during chick neurulation
59. LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for MNs
60. MN-derived retinoid signaling specifies the subtype identity of spinal MNs
61. Neural induction and regionalisation in the chick embryo
62. Early posterior neural tissue is induced by FGF in the chick embryo
63. Initiation of neural induction by FGF signalling before gastrulation
64. Altered segmental identity and abnormal migration of MNs in mice lacking Hoxb-1
65. Diversity and pattern in the developing spinal cord
66. Increased apoptosis of motoneurons and altered somatotopic maps in the brachial spinal cord of Hoxc-8-deficient mice
67. Topographic organization of embryonic MNs defined by expression of LIM homeobox genes
68. An early requirement for FGF signalling in the acquisition of neural cell fate in the chick embryo