Atherosclerosis modified

Circulation Research

Volumn 89, Issue 2, 2001, Pages 102-104

  Attie, Alan D ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Dyslipidemia; Epistatis; Hypercholesterolemia; Inflammation; Modifier genes

Indexed keywords

APOLIPOPROTEIN A; CHOLESTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR;

ATHEROSCLEROSIS; DNA MODIFICATION; DYSLIPIDEMIA; EDITORIAL; GENE SEQUENCE; HUMAN; LIPOPROTEIN BLOOD LEVEL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

EID: 0035920266     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/res.89.2.102     Document Type: Editorial

References (19)

1. Modifier genes in mice and humans
2. Phenotypes of patients with "simple" mendelian disorders are complex traits: Thresholds, modifiers, and systems dynamics
3. Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice
4. Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis
5. Genetic locus in mice that blocks the development of atherosclerosis despite extreme hyperlipidemia
6. Experimental strategies for the genetic dissection of complex traits in animal models
7. Atherosclerosis: An inflammatory disease
8. Treatment of insulin resistance with peroxisome proliferator-activated receptor γ agonists
9. PPAR γ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
10. A PPAR γ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis
11. Structural requirements of ligands for the oxysterol liver X receptors LXRα and LXRβ
12. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
13. Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase
14. Evidence for a dominant gene that suppresses hypercholesterolemia in a family with defective low density lipoprotein receptors
15. A cholesterol-lowering gene maps to chromosome 13q
16. Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein
17. Genetic identification of Mom-l, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
18. The MomlAKR intestinal tumor resistance region consists of P1a2g2a and a locus distal to D4 Mit64
19. Chemoprevention of spontaneous intestinal adenomas in the Apc Min mouse model by the nonsteroidal anti-inflammatory drug piroxicam