Investigation of the effects of YM-31636, a novel 5-HT3 receptor agonist, on defecation in normal and constipated ferrets

European Journal of Pharmacology

Volumn 424, Issue 2, 2001, Pages 151-157

  Ito, Hiroyuki ^a   Kiso, Tetsuo ^a   Yuki, Hidenobu ^a   Naitoh, Yuki ^a   Miyata, Keiji ^a   Iwaoka, Kiyoshi ^a   Yamaguchi, Tokio ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

5 HT3 receptor agonist; Constipation; Defecation; Diarrhea; Emesis; YM 31636

Indexed keywords

2 (1H IMIDAZOL 4 YLMETHYL) 8H INDENO[1,2 D]THIAZOLE MONOFURAMATE; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRIMONIDINE; FUMARIC ACID DERIVATIVE; LAXATIVE; MORPHINE; PICOSULFATE SODIUM; RAMOSETRON; SEROTONIN 3 AGONIST; SEROTONIN 3 ANTAGONIST; UNCLASSIFIED DRUG; YM 31636;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLON MOTILITY; COMPARATIVE STUDY; CONSTIPATION; CONTROLLED STUDY; DEFECATION; DIARRHEA; DOSE TIME EFFECT RELATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; FECES; FERRET; MALE; NONHUMAN; PRIORITY JOURNAL; VOMITING; WATER CONTENT;

ANIMALS; CONSTIPATION; DEFECATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FECES; FERRETS; MALE; NAUSEA; PICOLINES; PYRROLES; SEROTONIN AGONISTS; THIAZOLES; TIME FACTORS; VOMITING; WATER;

EID: 0035919609     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)01147-5     Document Type: Article

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