Enhanced reporter gene expression in the rat brain from helper virus-free HSV-1 vectors packaged in the presence of specific mutated HSV-1 proteins that affect the virion

Molecular Brain Research

Volumn 90, Issue 1, 2001, Pages 1-16

  Yang, Tianzhong ^a   Zhang, Guo rong ^a   Zhang, Wei ^a   Sun, Mei ^a   Wang, Xiaodan ^a   Geller, Alfred I ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Gene transfer; Herpes simplex virus vector; Long term expression; Neurofilament promoter; Protein kinase; VP16

Indexed keywords

MUTANT PROTEIN; PROTEIN KINASE; RNA; VIRUS PROTEIN; VIRUS VECTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRAIN; CELL STRAIN BHK; CONTROLLED STUDY; CORPUS STRIATUM; COSMID VECTOR; ENZYME ACTIVITY; GENE EXPRESSION; GENE TRANSFER; HELPER VIRUS; HERPES SIMPLEX VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; REPORTER GENE; RNA METABOLISM; VIRION;

ANIMALS; BETA-GALACTOSIDASE; BRAIN; CELL LINE; COSMIDS; CRICETINAE; FIBROBLASTS; GENE EXPRESSION REGULATION, VIRAL; GENES, REPORTER; GENES, SYNTHETIC; GENETIC VECTORS; HERPES SIMPLEX VIRUS PROTEIN VMW65; HERPESVIRUS 1, HUMAN; KIDNEY; LAC OPERON; MALE; MESOCRICETUS; MORPHOGENESIS; MUTATION; PC12 CELLS; PEPTIDES, CYCLIC; PROMOTER REGIONS (GENETICS); PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; VIRAL PROTEINS; VIRION;

HERPES; HUMAN HERPESVIRUS 1;

EID: 0035918481     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(01)00059-6     Document Type: Article

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