Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP

Brain Research

Volumn 916, Issue 1-2, 2001, Pages 211-221

  Shirane, Masatoshi ^a   Nakamura, Kazuo ^a  

^a NIPPON ROCHE RESEARCH CENTER   (Japan)

Author keywords

Aniracetam; Dopamine and serotinin release; Mecamylamine; Mesocortical pathway; Microdialysis; N anisoyl aminobutyric acid; Stroke prone spontaneously hypertensive rat

Indexed keywords

ANIRACETAM; DOPAMINE; DRUG METABOLITE; MECAMYLAMINE; N ANISOYL 4 AMINOBUTYRIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NICOTINIC RECEPTOR; PRESYNAPTIC RECEPTOR; RO 13 6680; SEROTONIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DOPAMINE RELEASE; DORSAL RAPHE NUCLEUS; DRUG EFFECT; DRUG MECHANISM; MALE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; SEROTONIN RELEASE; SPONTANEOUSLY HYPERTENSIVE RAT; VENTRAL TEGMENTUM;

ACETYLCHOLINE; ANIMALS; ANISOLES; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EXTRACELLULAR SPACE; GLUTAMIC ACID; HYDROXYBENZOIC ACIDS; MALE; MECAMYLAMINE; MICRODIALYSIS; NICOTINIC ANTAGONISTS; NOOTROPIC AGENTS; PREFRONTAL CORTEX; PRESYNAPTIC TERMINALS; PYRROLIDINONES; RAPHE NUCLEI; RATS; RATS, INBRED SHR; RECEPTORS, CHOLINERGIC; RECEPTORS, GLUTAMATE; SEROTONIN; VENTRAL TEGMENTAL AREA;

EID: 0035914208     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02939-0     Document Type: Article

References (48)

1. The 5-HT1A receptor selective ligands, (R)-8-OH-DPAT and (S)-UH-301, differentially affect the activity of midbrain dopamine neurons
2. (R)-8-OH-DPAT preferentially increases dopamine release in rat medial prefrontal cortex
3. Effect of AMPA receptor modulators on hippocampal and cortical function
4. Modulation of dopamine efflux in the nucleus accumbens after cholinergic stimulation of the ventral tegmental area in intact, pedunculopontine tegmental nucleus-lesioned, and laterodorsal tegmental nucleus-lesioned rats
5. Ultrastructural localization of the serotonin 2A receptor in dopaminergic neurons in the ventral tegmental area
6. Dopamine D2 receptor-mediated regulation of serotonin extracellular concentration in the dorsal raphe nucleus of freely moving rats
7. Systemic nicotine stimulates dopamine release in nucleus accumbens: Re-evaluation of the role of N-methyl-D-aspartate receptors in the ventral tegmental area
8. Oxiracetam and aniracetam increase acetylcholine release from the rat hippocampus in vivo
9. Role of 5-HT in stress, anxiety, and depression
10. Serotonin microinfusion into the ventral tegmental area increases accumbens dopamine release
11. Ionotropic glutamate receptor modulation preferentially affects NMDA receptor expression in rat hippocampus
12. Regulation of the mesocorticolimbic dopamine system by glutamic acid receptor subtypes
13. Brain mechanisms of emotion and emotional learning
14. Mesocorticolimbic dopaminergic network: Functional and regulatory roles
15. Metabotropic glutamate receptors modulate serotonin release in the rat periaqueductal gray matter
16. Pharmacology of aniracetam: A novel pyrrolidinone derivative with cognitive enhancing activity
17. A study of the N-methyl-D-aspartate antagonistic properties of anticholinergic drugs
18. The depletion of brain serotonin levels by para-chlorophenylalanine administration significantly alters the activity of midbrain dopamine cells in rats: An extracellular single cell recording study
19. Central cholinergic pathways in the rat: An overview based on alternative nomenclature (Ch1-Ch6)
20. Effects of nicotine and mecamylamine on rat dorsal raphe neurons
21. Ventral tegmental area 5-HT receptors: Mesolimbic dopamine release and behavioural studies
22. Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism
23. Serotonergic mechanisms involved in the attentional and vigilance task performance of rats and the palliative action of aniracetam
24. Impulsivity and AMPA receptors: Aniracetam ameliorates impulsive behavior induced by a blockade of AMPA receptors in rats
25. Apomorphine-induced hypo-attention in rats and reversal of the choice performance impairment by aniracetam
26. Scopolamine model of delirium in rats and reversal of the performance impairment by aniracetam
27. Activation of the reticulothalamic cholinergic pathway by the major metabolites of aniracetam
28. Site-specific activation of dopamine and serotonin transmission in the mesocorticolimbic pathway of rats by aniracetam
29. Antidepressive effects of aniracetam and its mode of action in behavioral despair paradigm in rats
30. Condition-independent sensitization of locomotor stimulation and mesocortical dopamine release following chronic nicotine treatment in the rat
31. Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area
32. Pharmacokinetics of aniracetam and its metabolites in rat brain
33. Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat
34. Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: An in situ hybridization study
35. Analysis of mecamylamine stereoisomers on human nicotinic receptor subtypes
36. Aniracetam, 1-BCP and cyclothiazide differentially modulate the function of NMDA and AMPA receptors mediating enhancement of noradrenaline release in rat hippocampal slices
37. Serotonin-dopamine interaction in the rat ventral tegmental area: An electrophysiological study in vivo
38. Glutamate is a cotransmitter in ventral midbrain dopamine neurons
39. Nicotinic receptors modulating somatodendritic and terminal dopamine release differ pharmacologically
40. Effects of systemic nicotine on serotonin release in rat brain
41. N-Methyl-D-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens
42. Group II metabotropic glutamate receptors are a common target of N-anisoyl-GABA and 1S,3R-ACPD in enhancing ACh release in the prefrontal cortex of freely moving SHRSP
43. Receptor systems participating in nicotine-specific effects
44. Differential effect of NMDA on extracellular serotonin in rat midbrain raphe and forebrain sites
45. Anatomy of the serotonergic system
46. Effect of nicotine on extracellular levels of neurotransmitters assessed by microdialysis in various brain regions: Role of glutamic acid
47. Presynaptic nicotinic ACh receptors