Spontaneously immortalized cell lines obtained from adult Atm null mice retain sensitivity to ionizing radiation and exhibit a mutational pattern suggestive of oxidative stress

Oncogene

Volumn 20, Issue 32, 2001, Pages 4291-4297

  Gage, Blythe M ^a   Alroy, Daniel ^a   Shin, Chi Y ^a   Ponomareva, Olga N ^a   Dhar, Sonu ^b   Sharma, Girdhar G ^b   Pandita, Tej K ^b   Thayer, Mathew J ^a   Turker, Mitchell S ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b Columbia University ^*  (United States)

Author keywords

Immortalized Atm null cells; Ionizing radiation; Mutagenesis oxidative stress

Indexed keywords

ATM PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL IMMORTALIZATION; CELL LINE; GENE LOCUS; GENE MUTATION; IONIZING RADIATION; MOUSE; MUTAGENICITY; NONHUMAN; NULL CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY;

ANIMALS; ATAXIA TELANGIECTASIA; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE, TRANSFORMED; CELL SURVIVAL; CHROMOSOME ABERRATIONS; DNA-BINDING PROTEINS; LOSS OF HETEROZYGOSITY; METAPHASE; MICE; MICE, KNOCKOUT; MUTAGENESIS; MUTATION; OXIDATIVE STRESS; PROTEIN-SERINE-THREONINE KINASES; RADIATION TOLERANCE; RADIATION, IONIZING; TUMOR SUPPRESSOR PROTEINS;

EID: 0035913157     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1204509     Document Type: Article

References (34)