Localization of the human mGluR4 gene within an epilepsy susceptibility locus

Molecular Brain Research

Volumn 87, Issue 1, 2001, Pages 109-116

  Wong, C Guin Ting ^a   Scherer, Stephen W ^a,c   Snead Iii, O Carter ^a,c   Hampson, David R ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Epilepsy; Human mGluR4 gene; Localization; Mapping; Structure

Indexed keywords

CONTIG; METABOTROPIC RECEPTOR; PROTEIN G;

ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 6; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCATION; GENE MAPPING; GENE STRUCTURE; HISTOCOMPATIBILITY COMPLEX; HUMAN; HUMAN CELL; INTRON; MALE; MYOCLONUS EPILEPSY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEIZURE SUSCEPTIBILITY; SEQUENCE TAGGED SITE;

CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 6; EXONS; GENE LIBRARY; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTRONS; MALE; MYOCLONIC EPILEPSY, JUVENILE; RECEPTORS, METABOTROPIC GLUTAMATE;

BACTERIA (MICROORGANISMS);

EID: 0035910946     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(00)00283-7     Document Type: Article

References (30)

1. Up-regulation of the metabotropic glutamate receptor mGluR4 in hippocampal neurons with reduced seizure vulnerability
2. Status epilepticus-induced alterations in metabotropic glutamate receptor expression in young and adult rats
3. Assignment of the human metabotropic glutamate receptor gene GRM4 to chromosome 6 ba1nd p21.3 by radiation hybrid mapping
4. A metabotropic glutamate receptor variant functions as a taste receptor
5. Genomic sequencing
6. Mapping and positional cloning of common idiopathic generalized epilepsies: Juvenile myoclonus epilepsy and childhood absence epilepsy
7. Molecular cloning, functional expression and pharmacological characterization of the human metabotropic glutamate receptor type 4
8. (R,S)-4-phosponophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsant and neuro-protective in vivo
9. Human gamma-aminobutyric acid B receptor gene: Complementary DNA cloning, expression, chromosomal location, and genomic organization
10. Association of HLA class II alleles in patients with juvenile myoclonic epilepsy compared with patients with other forms of adolescent-onset generalized epilepsy
11. Reproducibility and complications in gene searches: Linkage on chromosome 6, heterogeneity, association, and maternal inheritance in juvenile myoclonic epilepsy
12. The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6
13. G-protein-independent signaling mediated by metabotropic glutamate receptors
14. Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors
15. Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate
16. Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor
17. Mapping, genomic structure, and polymorphisms of the human GABABR1 receptor gene: Evaluation of its involvement in idiopathic generalized epilepsy
18. Neurotransmitter receptors I. The metabotropic glutamate receptors: Structure and functions
19. New perspectives for the development of selective metabotropic glutamate receptor ligands
20. Immunocytochemical localization of subtype 4a metabotropic glutamate receptor in the rat and mouse basal ganglia
21. Refined mapping of the epilepsy susceptibility locus EJM1 on chromosome 6
22. The human metabotropic glutamate receptor 8 (GRM8) gene: A disproportionately large gene located at 7q31.3-q32.1
23. Differential presynaptic localization of metabotropic glutamate receptor subtypes in rat hippocampus
24. A receptor: A critical role for mGluR4
25. Prolonged anticonvulsant activity of mGluR agonist in inferior colliculus of the genetically epileptic prone rat
26. Roles of metabotropic glutamate receptor subtypes in modulation of pentylenetetreazole-induced seizure activity in mice
27. Cloning and characterization of a metabotropic glutamate receptor, mGluR4b
28. Induction or protection of limbic seizures in mice by mGluR subtype selective agonists