Chemoprevention of intestinal tumorigenesis by nabumetone: Induction of apoptosis and Bcl-2 downregulation

British Journal of Cancer

Volumn 84, Issue 10, 2001, Pages 1412-1416

  Roy, H K ^a   Karoski, W J ^a   Ratashak, A ^a   Smyrk, T C ^b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Apoptosis; Colon cancer; Nonsteroidal anti inflammatory drugs

Indexed keywords

NABUMETONE; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER PREVENTION; CARCINOGENESIS; COLON MUCOSA; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG MECHANISM; GENE INDUCTION; INTESTINE CANCER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADENOMATOUS POLYPOSIS COLI; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTICARCINOGENIC AGENTS; APOPTOSIS; BUTANONES; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GENES, BCL-2; HUMANS; INTESTINAL NEOPLASMS; MICE; MICE, MUTANT STRAINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

EID: 0035906809     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2001.1807     Document Type: Article

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