Quasi-irreversible binding of agonist to β-adrenoceptors and formation of non-dissociating receptor-Gs complex in the absence of guanine nucleotides

European Journal of Pharmacology

Volumn 425, Issue 3, 2001, Pages 181-188

  Onaran, H Ongun ^a   Gurdal, Hakan ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Adrenoceptor; G protein; G protein receptor interaction; Irreversible complex; Ternary complex

Indexed keywords

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUFFER; DETERGENT; GUANINE NUCLEOTIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE DIPHOSPHATE; IODOPINDOLOL; ISOPRENALINE; PINDOLOL; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ANALYTIC METHOD; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG BINDING; DRUG RECEPTOR BINDING; GEL PERMEATION CHROMATOGRAPHY; GUINEA PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOBLOTTING; LUNG PARENCHYMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; WESTERN BLOTTING;

ADRENERGIC BETA-AGONISTS; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; DOSE-RESPONSE RELATIONSHIP, DRUG; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; GUANINE NUCLEOTIDES; GUANOSINE DIPHOSPHATE; GUINEA PIGS; IODINE RADIOISOTOPES; ISOPROTERENOL; LUNG; MACROMOLECULAR SUBSTANCES; MEMBRANES; PINDOLOL; RECEPTORS, ADRENERGIC, BETA; TIME FACTORS;

EID: 0035903022     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)01180-3     Document Type: Article

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