The Stoichiometry of Trimeric SIV Glycoprotein Interaction with CD4 Differs from That of Anti-envelope Antibody Fab Fragments

Journal of Biological Chemistry

Volumn 276, Issue 46, 2001, Pages 42667-42676

  Kim, Mikyung ^a   Chen, Bing ^b   Hussey, Rebecca E ^a   Chishti, Yasmin ^a   Montefiori, David ^c   Hoxie, James A ^d   Byron, Olwyn ^e   Campbell, Gordon ^e   Harrison, Stephen C ^b   Reinherz, Ellis L ^a,f  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

^f DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; PROTEINS; SIZE EXCLUSION CHROMATOGRAPHY; STOICHIOMETRY; VIRUSES;

ULTRACENTRIFUGATION;

BIOCHEMISTRY;

CD4 ANTIGEN; GLYCOPROTEIN GP 140; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; PROTEIN PRECURSOR; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN; AMINO ACID; GLYCOPROTEIN; LIGAND; ONCOPROTEIN; TRANSMEMBRANE PROTEIN, SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS FUSION PROTEIN;

AMINO ACID ANALYSIS; ANIMAL CELL; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; GEL PERMEATION CHROMATOGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNITY; LYMPHOID CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIMIAN IMMUNODEFICIENCY VIRUS; STOICHIOMETRY; ULTRACENTRIFUGATION; CHEMISTRY; CHROMATOGRAPHY; DIMERIZATION; HUMAN; KINETICS; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; STATISTICAL MODEL; SURFACE PLASMON RESONANCE; TIME; WESTERN BLOTTING;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; RNA VIRUSES; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

AMINO ACIDS; ANTIGENS, CD4; BINDING SITES; BLOTTING, WESTERN; CHROMATOGRAPHY; DIMERIZATION; GENE PRODUCTS, ENV; GLYCOPROTEINS; HIV; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; KINETICS; LIGANDS; MODELS, STATISTICAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RETROVIRIDAE PROTEINS, ONCOGENIC; SURFACE PLASMON RESONANCE; TIME FACTORS; ULTRACENTRIFUGATION; VIRAL FUSION PROTEINS;

EID: 0035900737     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104166200     Document Type: Article

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