Comparison of base-excision repair capacity in proliferating and differentiated PC 12 cells following acute challenge with dieldrin

Free Radical Biology and Medicine

Volumn 31, Issue 10, 2001, Pages 1272-1278

  Stedeford, Todd ^a   Cardozo Pelaez, Fernando ^a   Nemeth, Nicole ^a   Song, Shijie ^a,b   Harbison, Raymond D ^b   Sanchez Ramos, Juan ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

8 Hydroxy 2 deoxyguanosine; DNA Repair; Free radicals; Neurodegeneration; Organochlorine pesticides

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DIELDRIN; DNA BASE; DNA GLYCOSYLTRANSFERASE; MONOAMINE; NERVE GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DEGENERATION; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DOPAMINERGIC NERVE CELL; ELECTRON TRANSPORT; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME REGULATION; EXCISION REPAIR; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; BASE COMPOSITION; CELL DIFFERENTIATION; CELL DIVISION; DEOXYGUANOSINE; DIELDRIN; DNA DAMAGE; DNA REPAIR; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; INSECTICIDES; L-LACTATE DEHYDROGENASE; N-GLYCOSYL HYDROLASES; NERVE GROWTH FACTOR; NEURONS; PC12 CELLS; RATS; TUMOR CELLS, CULTURED;

EID: 0035890030     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00715-8     Document Type: Article

References (40)

1. Overview of human exposure to dieldrin residues in the environment and current trends of residue levels in tissue
2. Dopamine and norepinephrine depletion in ring doves fed DDE, dieldrin, and Aroclor 1254
3. Toxic, neurochemical and behavioral effects of dieldrin exposure in mallard ducks
4. Dieldrin and DA neuron toxicity
5. The in vitro effect of dieldrin on respiration of rat liver mitochondria
6. Formation of 8-hydroxy(deoxy)guanosine and generation of strand breaks at guanine residues in DNA by singlet oxygen
7. Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues
8. Oxidative processes and antioxidative defense mechanisms in the aging brain
9. Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase
10. Regulation and expression of the adaptive response to alkylating agents
11. Increased nuclear DNA oxidation in the brain in Alzheimer's disease
12. An assessment of oxidative damage to proteins, lipids, and DNA in brain from patients with Alzheimer's disease
13. Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
14. Marker of oxyradical-mediated DNA damage (8-hydroxy-2′-deoxyguanosine) is increased in nigro-striatum of parkinson's disease brain
15. Decreased base excision repair and increased helicase activity in Alzheimer's disease brain
16. DNA damage, repair and antioxidant systems in brain regions: A correlative study
17. Colorimetric measurement of lactic dehydrogenase activity of body fluids
18. Attenuation of age-dependent oxidative damage to DNA and protein in brainstem of Tg Cu/Zn SOD mice
19. Measurement of protein using bicinchoninic acid
20. Toxicity of dieldrin for dopaminergic neurons in mesencephalic cultures
21. Parkinson's disease and Alzheimer's disease: Hypersensitivity to X rays in cultured cell lines
22. Hypersensitivity to DNA-damaging agents in abiotrophies: A new explanation for degeneration of neurons, photoreceptors, and muscle in Alzheimer, Parkinson and Huntington diseases, retinitis pigmentosa, and Duchenne muscular dystrophy
23. DNA damage and chronic neuronal degenerations
24. Changes in levels of 8-hydroxyguanine in DNA, its repair and OGG1 mRNA in rat lungs after intratracheal administration of diesel exhaust particles
25. Demonstration of DNA repair in normal and neoplastic tissues after treatment with proximate chemical carcinogens and ultraviolet radiation
26. Persistence of O6-ethylguanine in rat-brain DNA: Correlation with nervous system-specific carcinogenesis by ethylnitrosourea
27. Chemical carcinogenesis in the nervous system. Preferential accumulation of O6-methylguanine in rat brain deoxyribonucleic acid during repetitive administration of N-methyl-N-nitrosourea
28. The role of DNA lesions in the processes leading to aging in mice
29. A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
30. Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium
31. Distribution of HEOD (Diledrin) in mammals: II. Some applications of the preliminary model
32. Neurotoxic factors in Parkinson's Disease and related disorders
33. Chronic systemic pesticide exposure reproduces features of Parkinson's disease
34. Selective effects of dieldrin on the GABAA receptor-channel subunits expressed in human embryonic kidney cells
35. Ecogenetics of Parkinson's disease: Prevalence and environmental aspects in rural areas
36. Parkinson's disease and exposure to agricultural work and pesticide chemicals
37. Environmental antecedents of young-onset Parkinson's disease
38. Risk factors for Parkinson's disease
39. Parkinson's disease and brain levels of organochlorine pesticides
40. Diorthosubstituted polychlorinated biphenyls in caudate nucleus in Parkinson's disease