Molecular dynamics of HIV-1 reverse transcriptase indicates increased flexibility upon DNA binding

Proteins: Structure, Function and Genetics

Volumn 45, Issue 3, 2001, Pages 176-182

  Madrid, Marcela ^a   Lukin, Jonathan A ^b   Madura, Jeffry D ^c   Ding, Jianping ^d,e   Arnold, Edward ^d  

^a PITTSBURGH SUPERCOMPUTING CENTER   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

^c DUQUESNE UNIVERSITY   (United States)

^d RUTGERS UNIVERSITY   (United States)

^e INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

B factors refinement; Collective motions; Concerted; Correlated; HIV 1 RT; Molecular modeling

Indexed keywords

DNA; DOUBLE STRANDED DNA; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DNA BINDING; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DATABASES, PROTEIN; DNA-BINDING PROTEINS; HIV-1 REVERSE TRANSCRIPTASE; MODELS, MOLECULAR; PEPTIDE MAPPING; PROTEIN BINDING; PROTEIN CONFORMATION; THERMODYNAMICS; VIRAL PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0035889686     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.1137     Document Type: Article

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